Wallweber HJ - Search Results

1

Multiple novel classes of APRIL-specific receptor-blocking peptides isolated by phage display.

Gordon NC, Lien S, Johnson J, Wallweber HJ, Tran T, Currell B, Mathieu M, Quan C, Starovasnik MA, Hymowitz SG, Kelley RF. Gordon NC, et al. Among authors: wallweber hj. J Mol Biol. 2010 Feb 12;396(1):166-77. doi: 10.1016/j.jmb.2009.11.041. Epub 2009 Nov 26. J Mol Biol. 2010. PMID: 19945466

2

The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity.

Hymowitz SG, Compaan DM, Yan M, Wallweber HJ, Dixit VM, Starovasnik MA, de Vos AM. Hymowitz SG, et al. Among authors: wallweber hj. Structure. 2003 Dec;11(12):1513-20. doi: 10.1016/j.str.2003.11.009. Structure. 2003. PMID: 14656435 Free article.

3

Engineering an APRIL-specific B cell maturation antigen.

Patel DR, Wallweber HJ, Yin J, Shriver SK, Marsters SA, Gordon NC, Starovasnik MA, Kelley RF. Patel DR, et al. Among authors: wallweber hj. J Biol Chem. 2004 Apr 16;279(16):16727-35. doi: 10.1074/jbc.M312316200. Epub 2004 Feb 4. J Biol Chem. 2004. PMID: 14764606 Free article.

4

The crystal structure of a proliferation-inducing ligand, APRIL.

Wallweber HJ, Compaan DM, Starovasnik MA, Hymowitz SG. Wallweber HJ, et al. J Mol Biol. 2004 Oct 15;343(2):283-90. doi: 10.1016/j.jmb.2004.08.040. J Mol Biol. 2004. PMID: 15451660

5

Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding.

Hymowitz SG, Patel DR, Wallweber HJ, Runyon S, Yan M, Yin J, Shriver SK, Gordon NC, Pan B, Skelton NJ, Kelley RF, Starovasnik MA. Hymowitz SG, et al. Among authors: wallweber hj. J Biol Chem. 2005 Feb 25;280(8):7218-27. doi: 10.1074/jbc.M411714200. Epub 2004 Nov 12. J Biol Chem. 2005. PMID: 15542592 Free article.

6

Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.

Lee CV, Hymowitz SG, Wallweber HJ, Gordon NC, Billeci KL, Tsai SP, Compaan DM, Yin J, Gong Q, Kelley RF, DeForge LE, Martin F, Starovasnik MA, Fuh G. Lee CV, et al. Among authors: wallweber hj. Blood. 2006 Nov 1;108(9):3103-11. doi: 10.1182/blood-2006-03-011031. Epub 2006 Jul 13. Blood. 2006. PMID: 16840730 Free article.

7

Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.

Zobel K, Wang L, Varfolomeev E, Franklin MC, Elliott LO, Wallweber HJ, Okawa DC, Flygare JA, Vucic D, Fairbrother WJ, Deshayes K. Zobel K, et al. Among authors: wallweber hj. ACS Chem Biol. 2006 Sep 19;1(8):525-33. doi: 10.1021/cb600276q. ACS Chem Biol. 2006. PMID: 17168540

8

Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination.

Dueber EC, Schoeffler AJ, Lingel A, Elliott JM, Fedorova AV, Giannetti AM, Zobel K, Maurer B, Varfolomeev E, Wu P, Wallweber HJ, Hymowitz SG, Deshayes K, Vucic D, Fairbrother WJ. Dueber EC, et al. Among authors: wallweber hj. Science. 2011 Oct 21;334(6054):376-80. doi: 10.1126/science.1207862. Science. 2011. PMID: 22021857

9

Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

Flygare JA, Beresini M, Budha N, Chan H, Chan IT, Cheeti S, Cohen F, Deshayes K, Doerner K, Eckhardt SG, Elliott LO, Feng B, Franklin MC, Reisner SF, Gazzard L, Halladay J, Hymowitz SG, La H, LoRusso P, Maurer B, Murray L, Plise E, Quan C, Stephan JP, Young SG, Tom J, Tsui V, Um J, Varfolomeev E, Vucic D, Wagner AJ, Wallweber HJ, Wang L, Ware J, Wen Z, Wong H, Wong JM, Wong M, Wong S, Yu R, Zobel K, Fairbrother WJ. Flygare JA, et al. Among authors: wallweber hj. J Med Chem. 2012 May 10;55(9):4101-13. doi: 10.1021/jm300060k. Epub 2012 Mar 28. J Med Chem. 2012. PMID: 22413863 Free PMC article.

10

The crystal structure of the catalytic domain of the NF-κB inducing kinase reveals a narrow but flexible active site.

de Leon-Boenig G, Bowman KK, Feng JA, Crawford T, Everett C, Franke Y, Oh A, Stanley M, Staben ST, Starovasnik MA, Wallweber HJ, Wu J, Wu LC, Johnson AR, Hymowitz SG. de Leon-Boenig G, et al. Among authors: wallweber hj. Structure. 2012 Oct 10;20(10):1704-14. doi: 10.1016/j.str.2012.07.013. Epub 2012 Aug 23. Structure. 2012. PMID: 22921830 Free article.

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