Hikichi Y - Search Results

1

A mutation in beta-tubulin and a sustained dependence on androgen receptor signalling in a newly established docetaxel-resistant prostate cancer cell line.

Hara T, Ushio K, Nishiwaki M, Kouno J, Araki H, Hikichi Y, Hattori M, Imai Y, Yamaoka M. Hara T, et al. Among authors: hikichi y. Cell Biol Int. 2010 Jan 25;34(2):177-84. doi: 10.1042/CBI20090030. Cell Biol Int. 2010. PMID: 19947927

2

Selective androgen receptor modulator activity of a steroidal antiandrogen TSAA-291 and its cofactor recruitment profile.

Hikichi Y, Yamaoka M, Kusaka M, Hara T. Hikichi Y, et al. Eur J Pharmacol. 2015 Oct 15;765:322-31. doi: 10.1016/j.ejphar.2015.08.052. Epub 2015 Sep 1. Eur J Pharmacol. 2015. PMID: 26335395

3

Amelioration of sexual behavior and motor activity deficits in a castrated rodent model with a selective androgen receptor modulator SARM-2f.

Morimoto M, Amano Y, Oka M, Harada A, Fujita H, Hikichi Y, Tozawa R, Yamaoka M, Hara T. Morimoto M, et al. Among authors: hikichi y. PLoS One. 2017 Dec 7;12(12):e0189480. doi: 10.1371/journal.pone.0189480. eCollection 2017. PLoS One. 2017. PMID: 29216311 Free PMC article.

4

A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells.

Ishikawa Y, Gamo K, Yabuki M, Takagi S, Toyoshima K, Nakayama K, Nakayama A, Morimoto M, Miyashita H, Dairiki R, Hikichi Y, Tomita N, Tomita D, Imamura S, Iwatani M, Kamada Y, Matsumoto S, Hara R, Nomura T, Tsuchida K, Nakamura K. Ishikawa Y, et al. Among authors: hikichi y. Mol Cancer Ther. 2017 Feb;16(2):273-284. doi: 10.1158/1535-7163.MCT-16-0471. Epub 2016 Nov 30. Mol Cancer Ther. 2017. PMID: 27903753

5

Biologic Response of Colorectal Cancer Xenograft Tumors to Sequential Treatment with Panitumumab and Bevacizumab.

Taniguchi H, Baba Y, Sagiya Y, Gotou M, Nakamura K, Sawada H, Yamanaka K, Sakakibara Y, Mori I, Hikichi Y, Soeda J, Baba H. Taniguchi H, et al. Among authors: hikichi y. Neoplasia. 2018 Jul;20(7):668-677. doi: 10.1016/j.neo.2018.04.006. Epub 2018 May 23. Neoplasia. 2018. PMID: 29802988 Free PMC article.

6

LIGHT, a member of the TNF superfamily, induces morphological changes and delays proliferation in the human rhabdomyosarcoma cell line RD.

Hikichi Y, Matsui H, Tsuji I, Nishi K, Yamada T, Shintani Y, Onda H. Hikichi Y, et al. Biochem Biophys Res Commun. 2001 Dec 7;289(3):670-7. doi: 10.1006/bbrc.2001.6039. Biochem Biophys Res Commun. 2001. PMID: 11726199

7

Design and synthesis of selective CDK8/19 dual inhibitors: Discovery of 4,5-dihydrothieno[3',4':3,4]benzo[1,2-d]isothiazole derivatives.

Ono K, Banno H, Okaniwa M, Hirayama T, Iwamura N, Hikichi Y, Murai S, Hasegawa M, Hasegawa Y, Yonemori K, Hata A, Aoyama K, Cary DR. Ono K, et al. Among authors: hikichi y. Bioorg Med Chem. 2017 Apr 15;25(8):2336-2350. doi: 10.1016/j.bmc.2017.02.038. Epub 2017 Feb 22. Bioorg Med Chem. 2017. PMID: 28302507

8

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential.

Fujimoto J, Hirayama T, Hirata Y, Hikichi Y, Murai S, Hasegawa M, Hasegawa Y, Yonemori K, Hata A, Aoyama K, Cary DR. Fujimoto J, et al. Among authors: hikichi y. Bioorg Med Chem. 2017 Jun 15;25(12):3018-3033. doi: 10.1016/j.bmc.2017.03.049. Epub 2017 Mar 30. Bioorg Med Chem. 2017. PMID: 28392276

9

LIGHT, a member of the tumor necrosis factor ligand superfamily, prevents tumor necrosis factor-alpha-mediated human primary hepatocyte apoptosis, but not Fas-mediated apoptosis.

Matsui H, Hikichi Y, Tsuji I, Yamada T, Shintani Y. Matsui H, et al. Among authors: hikichi y. J Biol Chem. 2002 Dec 20;277(51):50054-61. doi: 10.1074/jbc.M206562200. Epub 2002 Oct 18. J Biol Chem. 2002. PMID: 12393901 Free article.

10

FBL2 regulates amyloid precursor protein (APP) metabolism by promoting ubiquitination-dependent APP degradation and inhibition of APP endocytosis.

Watanabe T, Hikichi Y, Willuweit A, Shintani Y, Horiguchi T. Watanabe T, et al. Among authors: hikichi y. J Neurosci. 2012 Mar 7;32(10):3352-65. doi: 10.1523/JNEUROSCI.5659-11.2012. J Neurosci. 2012. PMID: 22399757 Free PMC article.

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