Wong PE - Search Results

1

Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes.

Stewart ML, Burchmore RJ, Clucas C, Hertz-Fowler C, Brooks K, Tait A, Macleod A, Turner CM, De Koning HP, Wong PE, Barrett MP. Stewart ML, et al. Among authors: wong pe. Eukaryot Cell. 2010 Feb;9(2):336-43. doi: 10.1128/EC.00200-09. Epub 2009 Dec 4. Eukaryot Cell. 2010. PMID: 19966032 Free PMC article.

2

A molecular mechanism for eflornithine resistance in African trypanosomes.

Vincent IM, Creek D, Watson DG, Kamleh MA, Woods DJ, Wong PE, Burchmore RJ, Barrett MP. Vincent IM, et al. Among authors: wong pe. PLoS Pathog. 2010 Nov 24;6(11):e1001204. doi: 10.1371/journal.ppat.1001204. PLoS Pathog. 2010. PMID: 21124824 Free PMC article.

3

Trypanocidal furamidine analogues: influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns.

Ward CP, Wong PE, Burchmore RJ, de Koning HP, Barrett MP. Ward CP, et al. Among authors: wong pe. Antimicrob Agents Chemother. 2011 May;55(5):2352-61. doi: 10.1128/AAC.01551-10. Epub 2011 Mar 14. Antimicrob Agents Chemother. 2011. PMID: 21402852 Free PMC article.

4

Targeted delivery of compounds to Trypanosoma brucei using the melamine motif.

Chollet C, Baliani A, Wong PE, Barrett MP, Gilbert IH. Chollet C, et al. Among authors: wong pe. Bioorg Med Chem. 2009 Mar 15;17(6):2512-23. doi: 10.1016/j.bmc.2009.01.058. Epub 2009 Jan 31. Bioorg Med Chem. 2009. PMID: 19250832

5

A glucose transporter can mediate ribose uptake: definition of residues that confer substrate specificity in a sugar transporter.

Naula CM, Logan FJ, Wong PE, Barrett MP, Burchmore RJ. Naula CM, et al. Among authors: wong pe. J Biol Chem. 2010 Sep 24;285(39):29721-8. doi: 10.1074/jbc.M110.106815. Epub 2010 Jul 2. J Biol Chem. 2010. PMID: 20601430 Free PMC article.

6

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics.

Scott FJ, Khalaf AI, Giordani F, Wong PE, Duffy S, Barrett M, Avery VM, Suckling CJ. Scott FJ, et al. Among authors: wong pe. Eur J Med Chem. 2016 Jun 30;116:116-125. doi: 10.1016/j.ejmech.2016.03.064. Epub 2016 Mar 29. Eur J Med Chem. 2016. PMID: 27060763 Free PMC article.

7

Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif.

Klee N, Wong PE, Baragaña B, Mazouni FE, Phillips MA, Barrett MP, Gilbert IH. Klee N, et al. Among authors: wong pe. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4364-6. doi: 10.1016/j.bmcl.2010.06.070. Epub 2010 Jun 17. Bioorg Med Chem Lett. 2010. PMID: 20615694 Free PMC article.

8

Aryl phosphoramidates of 5-phospho erythronohydroxamic acid, a new class of potent trypanocidal compounds.

Ruda GF, Wong PE, Alibu VP, Norval S, Read KD, Barrett MP, Gilbert IH. Ruda GF, et al. Among authors: wong pe. J Med Chem. 2010 Aug 26;53(16):6071-8. doi: 10.1021/jm1004754. J Med Chem. 2010. PMID: 20666371 Free PMC article.

9

Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1.

Khalaf AI, Huggan JK, Suckling CJ, Gibson CL, Stewart K, Giordani F, Barrett MP, Wong PE, Barrack KL, Hunter WN. Khalaf AI, et al. Among authors: wong pe. J Med Chem. 2014 Aug 14;57(15):6479-94. doi: 10.1021/jm500483b. Epub 2014 Jul 29. J Med Chem. 2014. PMID: 25007262 Free PMC article.

10

Counterflow dielectrophoresis for trypanosome enrichment and detection in blood.

Menachery A, Kremer C, Wong PE, Carlsson A, Neale SL, Barrett MP, Cooper JM. Menachery A, et al. Among authors: wong pe. Sci Rep. 2012;2:775. doi: 10.1038/srep00775. Epub 2012 Oct 26. Sci Rep. 2012. PMID: 23105971 Free PMC article.

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