Kozlowski J - Search Results

1

Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis.

Min SH, Wang Y, Gonsiorek W, Anilkumar G, Kozlowski J, Lundell D, Fine JS, Grant EP. Min SH, et al. Among authors: kozlowski j. Biochem Biophys Res Commun. 2010 Jan 1;391(1):1080-6. doi: 10.1016/j.bbrc.2009.12.025. Epub 2009 Dec 14. Biochem Biophys Res Commun. 2010. PMID: 20004647

2

CCR2 and CXCR4 regulate peripheral blood monocyte pharmacodynamics and link to efficacy in experimental autoimmune encephalomyelitis.

Wang Y, Cui L, Gonsiorek W, Min SH, Anilkumar G, Rosenblum S, Kozlowski J, Lundell D, Fine JS, Grant EP. Wang Y, et al. Among authors: kozlowski j. J Inflamm (Lond). 2009 Nov 11;6:32. doi: 10.1186/1476-9255-6-32. J Inflamm (Lond). 2009. PMID: 19906300 Free PMC article.

3

A selective and potent CXCR3 antagonist SCH 546738 attenuates the development of autoimmune diseases and delays graft rejection.

Jenh CH, Cox MA, Cui L, Reich EP, Sullivan L, Chen SC, Kinsley D, Qian S, Kim SH, Rosenblum S, Kozlowski J, Fine JS, Zavodny PJ, Lundell D. Jenh CH, et al. Among authors: kozlowski j. BMC Immunol. 2012 Jan 10;13:2. doi: 10.1186/1471-2172-13-2. BMC Immunol. 2012. PMID: 22233170 Free PMC article.

4

Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.

Lunn CA, Reich EP, Fine JS, Lavey B, Kozlowski JA, Hipkin RW, Lundell DJ, Bober L. Lunn CA, et al. Among authors: kozlowski ja. Br J Pharmacol. 2008 Jan;153(2):226-39. doi: 10.1038/sj.bjp.0707480. Epub 2007 Oct 1. Br J Pharmacol. 2008. PMID: 17906679 Free PMC article. Review.

5

Triaryl bis-sulfones as a new class of cannabinoid CB2 receptor inhibitors: identification of a lead and initial SAR studies.

Lavey BJ, Kozlowski JA, Hipkin RW, Gonsiorek W, Lundell DJ, Piwinski JJ, Narula S, Lunn CA. Lavey BJ, et al. Among authors: kozlowski ja. Bioorg Med Chem Lett. 2005 Feb 1;15(3):783-6. doi: 10.1016/j.bmcl.2004.11.007. Bioorg Med Chem Lett. 2005. PMID: 15664857

6

A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo.

Lunn CA, Fine JS, Rojas-Triana A, Jackson JV, Fan X, Kung TT, Gonsiorek W, Schwarz MA, Lavey B, Kozlowski JA, Narula SK, Lundell DJ, Hipkin RW, Bober LA. Lunn CA, et al. Among authors: kozlowski ja. J Pharmacol Exp Ther. 2006 Feb;316(2):780-8. doi: 10.1124/jpet.105.093500. Epub 2005 Oct 28. J Pharmacol Exp Ther. 2006. PMID: 16258021

7

Cannabinoid CB(2)-selective inverse agonist protects against antigen-induced bone loss.

Lunn CA, Fine J, Rojas-Triana A, Jackson JV, Lavey B, Kozlowski JA, Hipkin RW, Lundell DJ, Bober L. Lunn CA, et al. Among authors: kozlowski ja. Immunopharmacol Immunotoxicol. 2007;29(3-4):387-401. doi: 10.1080/08923970701674997. Immunopharmacol Immunotoxicol. 2007. PMID: 18075852

8

Characterization of peripheral human cannabinoid receptor (hCB2) expression and pharmacology using a novel radioligand, [35S]Sch225336.

Gonsiorek W, Hesk D, Chen SC, Kinsley D, Fine JS, Jackson JV, Bober LA, Deno G, Bian H, Fossetta J, Lunn CA, Kozlowski JA, Lavey B, Piwinski J, Narula SK, Lundell DJ, Hipkin RW. Gonsiorek W, et al. Among authors: kozlowski ja. J Biol Chem. 2006 Sep 22;281(38):28143-51. doi: 10.1074/jbc.M602364200. Epub 2006 Jun 5. J Biol Chem. 2006. PMID: 16754676 Free article.

9

Non-aromatic A-ring replacement in the triaryl bis-sulfone CB2 receptor inhibitors.

Gilbert EJ, Zhou G, Wong MK, Tong L, Shankar BB, Huang C, Kelly J, Lavey BJ, McCombie SW, Chen L, Rizvi R, Dong Y, Shu Y, Kozlowski JA, Shih NY, Hipkin RW, Gonsiorek W, Malikzay A, Lunn CA, Favreau L, Lundell DJ. Gilbert EJ, et al. Among authors: kozlowski ja. Bioorg Med Chem Lett. 2010 Jan 15;20(2):608-11. doi: 10.1016/j.bmcl.2009.11.084. Epub 2009 Nov 22. Bioorg Med Chem Lett. 2010. PMID: 20005710

10

Expansion of SAR studies on triaryl bis sulfone cannabinoid CB2 receptor ligands.

Tong L, Shankar BB, Chen L, Rizvi R, Kelly J, Gilbert E, Huang C, Yang DY, Kozlowski JA, Shih NY, Gonsiorek W, Hipkin RW, Malikzay A, Lunn CA, Lundell DJ. Tong L, et al. Among authors: kozlowski ja. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6785-9. doi: 10.1016/j.bmcl.2010.08.126. Epub 2010 Aug 31. Bioorg Med Chem Lett. 2010. PMID: 20850969

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