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Page 1
The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2.
D'Alessandro PL, Corti C, Roth A, Ugolini A, Sava A, Montanari D, Bianchi F, Garland SL, Powney B, Koppe EL, Rocheville M, Osborne G, Perez P, de la Fuente J, De Los Frailes M, Smith PW, Branch C, Nash D, Watson SP. D'Alessandro PL, et al. Among authors: ugolini a. Bioorg Med Chem Lett. 2010 Jan 15;20(2):759-62. doi: 10.1016/j.bmcl.2009.11.032. Epub 2009 Nov 26. Bioorg Med Chem Lett. 2010. PMID: 20005096
Synthesis and pharmacological characterisation of 2,4-dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists.
Micheli F, Fabio RD, Cavanni P, Rimland JM, Capelli AM, Chiamulera C, Corsi M, Corti C, Donati D, Feriani A, Ferraguti F, Maffeis M, Missio A, Ratti E, Paio A, Pachera R, Quartaroli M, Reggiani A, Sabbatini FM, Trist DG, Ugolini A, Vitulli G. Micheli F, et al. Among authors: ugolini a. Bioorg Med Chem. 2003 Jan 17;11(2):171-83. doi: 10.1016/s0968-0896(02)00424-8. Bioorg Med Chem. 2003. PMID: 12470711
Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity.
Sakurai F, Yukawa T, Kina A, Murakami M, Takami K, Morimoto S, Seto M, Kamata M, Yamashita T, Nakashima K, Narita N, Bettini E, Ugolini A, Corsi M, Hasui T. Sakurai F, et al. Among authors: ugolini a. Bioorg Med Chem. 2022 Feb 15;56:116576. doi: 10.1016/j.bmc.2021.116576. Epub 2021 Dec 16. Bioorg Med Chem. 2022. PMID: 35051811 Free article.
Design and synthesis of 6-methylpyridin-2-one derivatives as novel and potent GluN2A positive allosteric modulators for the treatment of cognitive impairment.
Yukawa T, Yamashita T, Imaeda T, Kakei H, Hashizume S, Nakamura M, Daini M, Okabe A, Nakashima K, Harada A, Narita N, Bettini E, Ugolini A, Corsi M, Hasui T. Yukawa T, et al. Among authors: ugolini a. Bioorg Med Chem. 2023 Feb 1;79:117150. doi: 10.1016/j.bmc.2022.117150. Epub 2022 Dec 24. Bioorg Med Chem. 2023. PMID: 36640594 Free article.
Transient forebrain over-expression of CRF induces plasma corticosterone and mild behavioural changes in adult conditional CRF transgenic mice.
Vicentini E, Arban R, Angelici O, Maraia G, Perico M, Mugnaini M, Ugolini A, Large C, Domenici E, Gerrard P, Bortner D, Mansuy IM, Mangiarini L, Merlo-Pich E. Vicentini E, et al. Among authors: ugolini a. Pharmacol Biochem Behav. 2009 Jul;93(1):17-24. doi: 10.1016/j.pbb.2009.03.015. Epub 2009 Apr 7. Pharmacol Biochem Behav. 2009. PMID: 19358863
150 results