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Studies of congenic lines in the Brown Norway rat model of Th2-mediated immunopathological disorders show that the aurothiopropanol sulfonate-induced immunological disorder (Aiid3) locus on chromosome 9 plays a major role compared to Aiid2 on chromosome 10.
Mas M, Cavaillès P, Colacios C, Subra JF, Lagrange D, Calise M, Christen MO, Druet P, Pelletier L, Gauguier D, Fournié GJ. Mas M, et al. Among authors: lagrange d. J Immunol. 2004 May 15;172(10):6354-61. doi: 10.4049/jimmunol.172.10.6354. J Immunol. 2004. PMID: 15128826
The rat Toxo1 locus directs toxoplasmosis outcome and controls parasite proliferation and spreading by macrophage-dependent mechanisms.
Cavaillès P, Sergent V, Bisanz C, Papapietro O, Colacios C, Mas M, Subra JF, Lagrange D, Calise M, Appolinaire S, Faraut T, Druet P, Saoudi A, Bessieres MH, Pipy B, Cesbron-Delauw MF, Fournié GJ. Cavaillès P, et al. Among authors: lagrange d. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. doi: 10.1073/pnas.0506643103. Epub 2006 Jan 6. Proc Natl Acad Sci U S A. 2006. PMID: 16407112 Free PMC article.
The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development.
Colacios C, Casemayou A, Dejean AS, Gaits-Iacovoni F, Pedros C, Bernard I, Lagrange D, Deckert M, Lamouroux L, Jagodic M, Olsson T, Liblau RS, Fournié GJ, Saoudi A. Colacios C, et al. Among authors: lagrange d. J Exp Med. 2011 Oct 24;208(11):2183-91. doi: 10.1084/jem.20102191. Epub 2011 Sep 26. J Exp Med. 2011. PMID: 21948080 Free PMC article.
A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.
Cavailles P, Flori P, Papapietro O, Bisanz C, Lagrange D, Pilloux L, Massera C, Cristinelli S, Jublot D, Bastien O, Loeuillet C, Aldebert D, Touquet B, Fournié GJ, Cesbron-Delauw MF. Cavailles P, et al. Among authors: lagrange d. PLoS Pathog. 2014 Apr 3;10(4):e1004005. doi: 10.1371/journal.ppat.1004005. eCollection 2014 Apr. PLoS Pathog. 2014. PMID: 24699513 Free PMC article.
Rat chromosome 9 bears a major susceptibility locus for IgE response.
Mas M, Subra JF, Lagrange D, Pilipenko-Appolinaire S, Kermarrec N, Gauguier D, Druet P, Fournié GJ. Mas M, et al. Among authors: lagrange d. Eur J Immunol. 2000 Jun;30(6):1698-705. doi: 10.1002/1521-4141(200006)30:6<1698::AID-IMMU1698>3.0.CO;2-F. Eur J Immunol. 2000. PMID: 10898507 Free article.
A role for VAV1 in experimental autoimmune encephalomyelitis and multiple sclerosis.
Jagodic M, Colacios C, Nohra R, Dejean AS, Beyeen AD, Khademi M, Casemayou A, Lamouroux L, Duthoit C, Papapietro O, Sjöholm L, Bernard I, Lagrange D, Dahlman I, Lundmark F, Oturai AB, Soendergaard HB, Kemppinen A, Saarela J, Tienari PJ, Harbo HF, Spurkland A, Ramagopalan SV, Sadovnick DA, Ebers GC, Seddighzadeh M, Klareskog L, Alfredsson L, Padyukov L, Hillert J, Clanet M, Edan G, Fontaine B, Fournié GJ, Kockum I, Saoudi A, Olsson T. Jagodic M, et al. Among authors: lagrange d. Sci Transl Med. 2009 Dec 9;1(10):10ra21. doi: 10.1126/scitranslmed.3000278. Sci Transl Med. 2009. PMID: 20368159
39 results