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A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.
Okada H, Kunishima S, Hamaguchi M, Takagi A, Yamamoto K, Takamatsu J, Matsushita T, Saito H, Kojima T, Yamazaki T. Okada H, et al. Among authors: takamatsu j. Thromb Res. 2010 May;125(5):e246-50. doi: 10.1016/j.thromres.2009.11.029. Epub 2009 Dec 21. Thromb Res. 2010. PMID: 20022358
Comparison of the efficacy of ribavirin plus peginterferon alfa-2b for chronic hepatitis C infection in patients with and without coagulation disorders.
Honda T, Katano Y, Kuzuya T, Hayashi K, Ishigami M, Itoh A, Hirooka Y, Nakano I, Ishikawa T, Toyoda H, Kumada T, Yamamoto K, Matsushita T, Kojima T, Takamatsu J, Goto H. Honda T, et al. Among authors: takamatsu j. J Med Virol. 2013 Feb;85(2):228-34. doi: 10.1002/jmv.23444. Epub 2012 Nov 14. J Med Virol. 2013. PMID: 23160930
354 results