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Page 1
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization.
Porcelli AM, Ghelli A, Ceccarelli C, Lang M, Cenacchi G, Capristo M, Pennisi LF, Morra I, Ciccarelli E, Melcarne A, Bartoletti-Stella A, Salfi N, Tallini G, Martinuzzi A, Carelli V, Attimonelli M, Rugolo M, Romeo G, Gasparre G. Porcelli AM, et al. Among authors: gasparre g. Hum Mol Genet. 2010 Mar 15;19(6):1019-32. doi: 10.1093/hmg/ddp566. Epub 2009 Dec 22. Hum Mol Genet. 2010. PMID: 20028790
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.
Gasparre G, Porcelli AM, Bonora E, Pennisi LF, Toller M, Iommarini L, Ghelli A, Moretti M, Betts CM, Martinelli GN, Ceroni AR, Curcio F, Carelli V, Rugolo M, Tallini G, Romeo G. Gasparre G, et al. Proc Natl Acad Sci U S A. 2007 May 22;104(21):9001-6. doi: 10.1073/pnas.0703056104. Epub 2007 May 15. Proc Natl Acad Sci U S A. 2007. PMID: 17517629 Free PMC article.
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma.
Gasparre G, Hervouet E, de Laplanche E, Demont J, Pennisi LF, Colombel M, Mège-Lechevallier F, Scoazec JY, Bonora E, Smeets R, Smeitink J, Lazar V, Lespinasse J, Giraud S, Godinot C, Romeo G, Simonnet H. Gasparre G, et al. Hum Mol Genet. 2008 Apr 1;17(7):986-95. doi: 10.1093/hmg/ddm371. Epub 2007 Dec 21. Hum Mol Genet. 2008. PMID: 18156159
Molecular features of thyroid oncocytic tumors.
Gasparre G, Bonora E, Tallini G, Romeo G. Gasparre G, et al. Mol Cell Endocrinol. 2010 May 28;321(1):67-76. doi: 10.1016/j.mce.2010.02.022. Epub 2010 Feb 23. Mol Cell Endocrinol. 2010. PMID: 20184940 Review.
Mitochondrial metabolism and cancer.
Kurelac I, Romeo G, Gasparre G. Kurelac I, et al. Among authors: gasparre g. Mitochondrion. 2011 Jul;11(4):635-7. doi: 10.1016/j.mito.2011.03.012. Epub 2011 Apr 5. Mitochondrion. 2011. PMID: 21447406 No abstract available.
132 results