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Design, synthesis and preliminary biological evaluation of acridine compounds as potential agents for a combined targeted chemo-radionuclide therapy approach to melanoma.
Desbois N, Gardette M, Papon J, Labarre P, Maisonial A, Auzeloux P, Lartigue C, Bouchon B, Debiton E, Blache Y, Chavignon O, Teulade JC, Maublant J, Madelmont JC, Moins N, Chezal JM. Desbois N, et al. Among authors: debiton e. Bioorg Med Chem. 2008 Aug 15;16(16):7671-90. doi: 10.1016/j.bmc.2008.07.015. Epub 2008 Jul 10. Bioorg Med Chem. 2008. PMID: 18656367
Imidazonaphthyridine systems (part 2): Functionalization of the phenyl ring linked to the pyridine pharmacophore and its replacement by a pyridinone ring produces intriguing differences in cytocidal activity.
Masurier N, Debiton E, Jacquemet A, Bussière A, Chezal JM, Ollivier A, Tétégan D, Andaloussi M, Galmier MJ, Lacroix J, Canitrot D, Teulade JC, Gaudreault RC, Chavignon O, Moreau E. Masurier N, et al. Among authors: debiton e. Eur J Med Chem. 2012 Jun;52:137-50. doi: 10.1016/j.ejmech.2012.03.011. Epub 2012 Mar 20. Eur J Med Chem. 2012. PMID: 22503207
47 results