Chang TY - Search Results

1

Identification, SAR studies, and X-ray co-crystallographic analysis of a novel furanopyrimidine aurora kinase A inhibitor.

Coumar MS, Tsai MT, Chu CY, Uang BJ, Lin WH, Chang CY, Chang TY, Leou JS, Teng CH, Wu JS, Fang MY, Chen CH, Hsu JT, Wu SY, Chao YS, Hsieh HP. Coumar MS, et al. Among authors: chang cy, chang ty. ChemMedChem. 2010 Feb 1;5(2):255-67. doi: 10.1002/cmdc.200900339. ChemMedChem. 2010. PMID: 20039358

2

Aurora kinase A inhibitors: identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold.

Coumar MS, Wu JS, Leou JS, Tan UK, Chang CY, Chang TY, Lin WH, Hsu JT, Chao YS, Wu SY, Hsieh HP. Coumar MS, et al. Among authors: chang cy, chang ty. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1623-7. doi: 10.1016/j.bmcl.2008.01.068. Epub 2008 Jan 19. Bioorg Med Chem Lett. 2008. PMID: 18243698

3

A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors.

Lin WH, Song JS, Chang TY, Chang CY, Fu YN, Yeh CL, Wu SH, Huang YW, Fang MY, Lien TW, Hsieh HP, Chao YS, Huang SF, Tsai SF, Wang LM, Hsu JT, Chen YR. Lin WH, et al. Among authors: chang cy, chang ty. Anal Biochem. 2008 Jun 1;377(1):89-94. doi: 10.1016/j.ab.2008.02.027. Epub 2008 Mar 4. Anal Biochem. 2008. PMID: 18358823

4

Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.

Wu CH, Coumar MS, Chu CY, Lin WH, Chen YR, Chen CT, Shiao HY, Rafi S, Wang SY, Hsu H, Chen CH, Chang CY, Chang TY, Lien TW, Fang MY, Yeh KC, Chen CP, Yeh TK, Hsieh SH, Hsu JT, Liao CC, Chao YS, Hsieh HP. Wu CH, et al. Among authors: chang cy, chang ty. J Med Chem. 2010 Oct 28;53(20):7316-26. doi: 10.1021/jm100607r. J Med Chem. 2010. PMID: 20961149

5

Diosgenin, a plant-derived sapogenin, exhibits antiviral activity in vitro against hepatitis C virus.

Wang YJ, Pan KL, Hsieh TC, Chang TY, Lin WH, Hsu JT. Wang YJ, et al. Among authors: chang ty. J Nat Prod. 2011 Apr 25;74(4):580-4. doi: 10.1021/np100578u. Epub 2011 Mar 10. J Nat Prod. 2011. PMID: 21391660

6

A high-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors.

Lin WH, Song JS, Lien TW, Chang CY, Wu SH, Huang YW, Chang TY, Fang MY, Yen KJ, Chen CH, Chu CY, Hsieh HP, Chen YR, Chao YS, Hsu JT. Lin WH, et al. Among authors: chang cy, chang ty. Anticancer Res. 2012 Jan;32(1):147-51. Anticancer Res. 2012. PMID: 22213300

7

EGFR and myosin II inhibitors cooperate to suppress EGFR-T790M-mutant NSCLC cells.

Chiu HC, Chang TY, Huang CT, Chao YS, Hsu JT. Chiu HC, et al. Among authors: chang ty. Mol Oncol. 2012 Jun;6(3):299-310. doi: 10.1016/j.molonc.2012.02.001. Epub 2012 Feb 10. Mol Oncol. 2012. PMID: 22366308 Free PMC article.

8

Enhanced recombinant protein production and differential expression of molecular chaperones in sf-caspase-1-repressed stable cells after baculovirus infection.

Lai YK, Hsu JT, Chu CC, Chang TY, Pan KL, Lin CC. Lai YK, et al. Among authors: chang ty. BMC Biotechnol. 2012 Nov 7;12:83. doi: 10.1186/1472-6750-12-83. BMC Biotechnol. 2012. PMID: 23134743 Free PMC article.

9

The combination effects of licl and the active leflunomide metabolite, A771726, on viral-induced interleukin 6 production and EV-A71 replication.

Hung HC, Shih SR, Chang TY, Fang MY, Hsu JT. Hung HC, et al. Among authors: chang ty. PLoS One. 2014 Nov 20;9(11):e111331. doi: 10.1371/journal.pone.0111331. eCollection 2014. PLoS One. 2014. PMID: 25412347 Free PMC article.

10

Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor.

Yang S, Chen SJ, Hsu MF, Wu JD, Tseng CT, Liu YF, Chen HC, Kuo CW, Wu CS, Chang LW, Chen WC, Liao SY, Chang TY, Hung HH, Shr HL, Liu CY, Huang YA, Chang LY, Hsu JC, Peters CJ, Wang AH, Hsu MC. Yang S, et al. Among authors: chang ly, chang lw, chang ty. J Med Chem. 2006 Aug 10;49(16):4971-80. doi: 10.1021/jm0603926. J Med Chem. 2006. PMID: 16884309

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