Sirota M - Search Results

1

Autoimmune disease classification by inverse association with SNP alleles.

Sirota M, Schaub MA, Batzoglou S, Robinson WH, Butte AJ. Sirota M, et al. PLoS Genet. 2009 Dec;5(12):e1000792. doi: 10.1371/journal.pgen.1000792. Epub 2009 Dec 24. PLoS Genet. 2009. PMID: 20041220 Free PMC article.

2

CONTRAST: a discriminative, phylogeny-free approach to multiple informant de novo gene prediction.

Gross SS, Do CB, Sirota M, Batzoglou S. Gross SS, et al. Among authors: sirota m. Genome Biol. 2007;8(12):R269. doi: 10.1186/gb-2007-8-12-r269. Genome Biol. 2007. PMID: 18096039 Free PMC article.

3

A Classifier-based approach to identify genetic similarities between diseases.

Schaub MA, Kaplow IM, Sirota M, Do CB, Butte AJ, Batzoglou S. Schaub MA, et al. Among authors: sirota m. Bioinformatics. 2009 Jun 15;25(12):i21-9. doi: 10.1093/bioinformatics/btp226. Bioinformatics. 2009. PMID: 19477990 Free PMC article.

4

Drug discovery in a multidimensional world: systems, patterns, and networks.

Dudley JT, Schadt E, Sirota M, Butte AJ, Ashley E. Dudley JT, et al. Among authors: sirota m. J Cardiovasc Transl Res. 2010 Oct;3(5):438-47. doi: 10.1007/s12265-010-9214-6. Epub 2010 Jul 31. J Cardiovasc Transl Res. 2010. PMID: 20677029

5

Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association.

Chen R, Davydov EV, Sirota M, Butte AJ. Chen R, et al. Among authors: sirota m. PLoS One. 2010 Oct 22;5(10):e13574. doi: 10.1371/journal.pone.0013574. PLoS One. 2010. PMID: 21042586 Free PMC article.

6

Identifying a high fraction of the human genome to be under selective constraint using GERP++.

Davydov EV, Goode DL, Sirota M, Cooper GM, Sidow A, Batzoglou S. Davydov EV, et al. Among authors: sirota m. PLoS Comput Biol. 2010 Dec 2;6(12):e1001025. doi: 10.1371/journal.pcbi.1001025. PLoS Comput Biol. 2010. PMID: 21152010 Free PMC article.

7

Transmission distortion in Crohn's disease risk gene ATG16L1 leads to sex difference in disease association.

Liu LY, Schaub MA, Sirota M, Butte AJ. Liu LY, et al. Among authors: sirota m. Inflamm Bowel Dis. 2012 Feb;18(2):312-22. doi: 10.1002/ibd.21781. Epub 2011 May 25. Inflamm Bowel Dis. 2012. PMID: 21618365 Free PMC article.

8

The role of bioinformatics in studying rheumatic and autoimmune disorders.

Sirota M, Butte AJ. Sirota M, et al. Nat Rev Rheumatol. 2011 Jun 21;7(8):489-94. doi: 10.1038/nrrheum.2011.87. Nat Rev Rheumatol. 2011. PMID: 21691330

9

Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease.

Dudley JT, Sirota M, Shenoy M, Pai RK, Roedder S, Chiang AP, Morgan AA, Sarwal MM, Pasricha PJ, Butte AJ. Dudley JT, et al. Among authors: sirota m. Sci Transl Med. 2011 Aug 17;3(96):96ra76. doi: 10.1126/scitranslmed.3002648. Sci Transl Med. 2011. PMID: 21849664 Free PMC article.

10

Discovery and preclinical validation of drug indications using compendia of public gene expression data.

Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A, Sage J, Butte AJ. Sirota M, et al. Sci Transl Med. 2011 Aug 17;3(96):96ra77. doi: 10.1126/scitranslmed.3001318. Sci Transl Med. 2011. PMID: 21849665 Free PMC article.

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