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A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion.
Sharma J, Du M, Wong E, Mutyam V, Li Y, Chen J, Wangen J, Thrasher K, Fu L, Peng N, Tang L, Liu K, Mathew B, Bostwick RJ, Augelli-Szafran CE, Bihler H, Liang F, Mahiou J, Saltz J, Rab A, Hong J, Sorscher EJ, Mendenhall EM, Coppola CJ, Keeling KM, Green R, Mense M, Suto MJ, Rowe SM, Bedwell DM. Sharma J, et al. Among authors: rab a. Nat Commun. 2021 Jul 16;12(1):4358. doi: 10.1038/s41467-021-24575-x. Nat Commun. 2021. PMID: 34272367 Free PMC article.
Restoration of W1282X CFTR activity by enhanced expression.
Rowe SM, Varga K, Rab A, Bebok Z, Byram K, Li Y, Sorscher EJ, Clancy JP. Rowe SM, et al. Among authors: rab a. Am J Respir Cell Mol Biol. 2007 Sep;37(3):347-56. doi: 10.1165/rcmb.2006-0176OC. Epub 2007 May 31. Am J Respir Cell Mol Biol. 2007. PMID: 17541014 Free PMC article.
Cigarette smoke and CFTR: implications in the pathogenesis of COPD.
Rab A, Rowe SM, Raju SV, Bebok Z, Matalon S, Collawn JF. Rab A, et al. Am J Physiol Lung Cell Mol Physiol. 2013 Oct 15;305(8):L530-41. doi: 10.1152/ajplung.00039.2013. Epub 2013 Aug 9. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 23934925 Free PMC article. Review.
86 results