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The products of the reaction between 6-amine-1,3-dimethyl uracil and bis-chalcones induce cytotoxicity with massive vacuolation in HeLa cervical cancer cell line.
Solano JD, González-Sánchez I, Cerbón MA, Guzmán Á, Martínez-Urbina MA, Vilchis-Reyes MA, Martínez-Zuñiga EC, Alvarado C, Quintero A, Díaz E. Solano JD, et al. Among authors: martinez urbina ma. Eur J Med Chem. 2013 Feb;60:350-9. doi: 10.1016/j.ejmech.2012.12.021. Epub 2012 Dec 17. Eur J Med Chem. 2013. PMID: 23314048