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Syk: a novel target for treatment of inflammation in lung disease.
Sanderson MP, Lau CW, Schnapp A, Chow CW. Sanderson MP, et al. Among authors: schnapp a. Inflamm Allergy Drug Targets. 2009 Jun;8(2):87-95. doi: 10.2174/187152809788462626. Inflamm Allergy Drug Targets. 2009. PMID: 19530990 Review.
BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.
Lamb DJ, Wollin SL, Schnapp A, Bischoff D, Erb KJ, Bouyssou T, Guilliard B, Strasser C, Wex E, Blum S, Thaler E, Nickel H, Radmacher O, Haas H, Swantek JL, Souza D, Canfield M, White D, Panzenbeck M, Kashem MA, Sanville-Ross M, Kono T, Sewald K, Braun A, Obernolte H, Danov O, Schaenzle G, Rast G, Maier GM, Hoffmann M. Lamb DJ, et al. Among authors: schnapp a. J Pharmacol Exp Ther. 2016 Jun;357(3):554-61. doi: 10.1124/jpet.116.233155. Epub 2016 Apr 5. J Pharmacol Exp Ther. 2016. PMID: 27048659
Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization.
Baum P, Schmid R, Ittrich C, Rust W, Fundel-Clemens K, Siewert S, Baur M, Mara L, Gruenbaum L, Heckel A, Eils R, Kontermann RE, Roth GJ, Gantner F, Schnapp A, Park JE, Weith A, Quast K, Mennerich D. Baum P, et al. Among authors: schnapp a. PLoS One. 2010 Dec 10;5(12):e14272. doi: 10.1371/journal.pone.0014272. PLoS One. 2010. PMID: 21170314 Free PMC article.
59 results