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Page 1
Synthesis and optimization of hyaluronic acid-methotrexate conjugates to maximize benefit in the treatment of osteoarthritis.
Homma A, Sato H, Tamura T, Okamachi A, Emura T, Ishizawa T, Kato T, Matsuura T, Sato S, Higuchi Y, Watanabe T, Kitamura H, Asanuma K, Yamazaki T, Ikemi M, Kitagawa H, Morikawa T, Ikeya H, Maeda K, Takahashi K, Nohmi K, Izutani N, Kanda M, Suzuki R. Homma A, et al. Among authors: emura t. Bioorg Med Chem. 2010 Feb;18(3):1062-75. doi: 10.1016/j.bmc.2009.12.053. Epub 2009 Dec 28. Bioorg Med Chem. 2010. PMID: 20060728
Design and evaluation of new antipsoriatic antedrug candidates having 16-en-22-oxa-vitamin D3 structures.
Shimizu K, Kawase A, Haneishi T, Kato Y, Kinoshita K, Ohmori M, Furuta Y, Emura T, Kato N, Mitsui T, Yamaguchi K, Morita K, Sekiguchi N, Yamamoto T, Matsushita T, Shimaoka S, Sugita A, Morikawa K. Shimizu K, et al. Among authors: emura t. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3323-9. doi: 10.1016/j.bmcl.2006.03.014. Epub 2006 Apr 21. Bioorg Med Chem Lett. 2006. PMID: 16630723
Novel hyaluronic acid-methotrexate conjugates for osteoarthritis treatment.
Homma A, Sato H, Okamachi A, Emura T, Ishizawa T, Kato T, Matsuura T, Sato S, Tamura T, Higuchi Y, Watanabe T, Kitamura H, Asanuma K, Yamazaki T, Ikemi M, Kitagawa H, Morikawa T, Ikeya H, Maeda K, Takahashi K, Nohmi K, Izutani N, Kanda M, Suzuki R. Homma A, et al. Among authors: emura t. Bioorg Med Chem. 2009 Jul 1;17(13):4647-56. doi: 10.1016/j.bmc.2009.04.063. Epub 2009 May 3. Bioorg Med Chem. 2009. PMID: 19457673
Design and synthesis of an androgen receptor pure antagonist (CH5137291) for the treatment of castration-resistant prostate cancer.
Yoshino H, Sato H, Shiraishi T, Tachibana K, Emura T, Honma A, Ishikura N, Tsunenari T, Watanabe M, Nishimoto A, Nakamura R, Nakagawa T, Ohta M, Takata N, Furumoto K, Kimura K, Kawata H. Yoshino H, et al. Among authors: emura t. Bioorg Med Chem. 2010 Dec 1;18(23):8150-7. doi: 10.1016/j.bmc.2010.10.023. Epub 2010 Oct 15. Bioorg Med Chem. 2010. PMID: 21050768
Discovery of novel tetracyclic compounds as anaplastic lymphoma kinase inhibitors.
Kinoshita K, Ono Y, Emura T, Asoh K, Furuichi N, Ito T, Kawada H, Tanaka S, Morikami K, Tsukaguchi T, Sakamoto H, Tsukuda T, Oikawa N. Kinoshita K, et al. Among authors: emura t. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3788-93. doi: 10.1016/j.bmcl.2011.04.020. Epub 2011 Apr 22. Bioorg Med Chem Lett. 2011. PMID: 21561771
Lead Optimization and Avoidance of Reactive Metabolite Leading to PCO371, a Potent, Selective, and Orally Available Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist.
Nishimura Y, Esaki T, Isshiki Y, Furuta Y, Mizutani A, Kotake T, Emura T, Watanabe Y, Ohta M, Nakagawa T, Ogawa K, Arai S, Noda H, Kitamura H, Shimizu M, Tamura T, Sato H. Nishimura Y, et al. Among authors: emura t. J Med Chem. 2020 May 28;63(10):5089-5099. doi: 10.1021/acs.jmedchem.9b01743. Epub 2020 Feb 17. J Med Chem. 2020. PMID: 32022560
121 results