Pacholec M - Search Results

1

Fatal disseminated Mycobacterium haemophilum infection involving the central nervous system in a renal transplant recipient.

Pacholec M, Sami F, Newell K, El Atrouni W. Pacholec M, et al. J Clin Tuberc Other Mycobact Dis. 2020 Oct 19;21:100197. doi: 10.1016/j.jctube.2020.100197. eCollection 2020 Dec. J Clin Tuberc Other Mycobact Dis. 2020. PMID: 33294628 Free PMC article.

2

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.

Pacholec M, Bleasdale JE, Chrunyk B, Cunningham D, Flynn D, Garofalo RS, Griffith D, Griffor M, Loulakis P, Pabst B, Qiu X, Stockman B, Thanabal V, Varghese A, Ward J, Withka J, Ahn K. Pacholec M, et al. J Biol Chem. 2010 Mar 12;285(11):8340-51. doi: 10.1074/jbc.M109.088682. Epub 2010 Jan 8. J Biol Chem. 2010. PMID: 20061378 Free PMC article.

3

Formation of an aminoacyl-S-enzyme intermediate is a key step in the biosynthesis of chloramphenicol.

Pacholec M, Sello JK, Walsh CT, Thomas MG. Pacholec M, et al. Org Biomol Chem. 2007 Jun 7;5(11):1692-4. doi: 10.1039/b703356g. Epub 2007 Apr 26. Org Biomol Chem. 2007. PMID: 17520135

4

CouO and NovO: C-methyltransferases for tailoring the aminocoumarin scaffold in coumermycin and novobiocin antibiotic biosynthesis.

Pacholec M, Tao J, Walsh CT. Pacholec M, et al. Biochemistry. 2005 Nov 15;44(45):14969-76. doi: 10.1021/bi051599o. Biochemistry. 2005. PMID: 16274243

5

NovJ/NovK catalyze benzylic oxidation of a beta-hydroxyl tyrosyl-S-pantetheinyl enzyme during aminocoumarin ring formation in novobiocin biosynthesis.

Pacholec M, Hillson NJ, Walsh CT. Pacholec M, et al. Biochemistry. 2005 Sep 27;44(38):12819-26. doi: 10.1021/bi051297m. Biochemistry. 2005. PMID: 16171397

6

Characterization of the aminocoumarin ligase SimL from the simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway.

Pacholec M, Freel Meyers CL, Oberthür M, Kahne D, Walsh CT. Pacholec M, et al. Biochemistry. 2005 Mar 29;44(12):4949-56. doi: 10.1021/bi047303g. Biochemistry. 2005. PMID: 15779922

7

Mass spectrometric characterization of a three-enzyme tandem reaction for assembly and modification of the novobiocin skeleton.

Pi N, Meyers CL, Pacholec M, Walsh CT, Leary JA. Pi N, et al. Among authors: pacholec m. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10036-41. doi: 10.1073/pnas.0403526101. Epub 2004 Jun 24. Proc Natl Acad Sci U S A. 2004. PMID: 15218104 Free PMC article.

8

Synthesis of proposed oxidation-cyclization-methylation intermediates of the coumarin antibiotic biosynthetic pathway.

Tao J, Hu S, Pacholec M, Walsh CT. Tao J, et al. Among authors: pacholec m. Org Lett. 2003 Sep 4;5(18):3233-6. doi: 10.1021/ol035101r. Org Lett. 2003. PMID: 12943395

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