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A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys.
Bone. 2010 Apr;46(4):1082-8. doi: 10.1016/j.bone.2010.01.370. Epub 2010 Jan 18.
Bone. 2010.
PMID: 20080223
Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis).
Fajardo RJ, Manoharan RK, Pearsall RS, Davies MV, Marvell T, Monnell TE, Ucran JA, Pearsall AE, Khanzode D, Kumar R, Underwood KW, Roberts B, Seehra J, Bouxsein ML.
Fajardo RJ, et al.
Bone. 2010 Jan;46(1):64-71. doi: 10.1016/j.bone.2009.09.018. Epub 2009 Sep 23.
Bone. 2010.
PMID: 19781677
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A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesis.
Bridges KG, Chopra R, Lin L, Svenson K, Tam A, Jin G, Cowling R, Lovering F, Akopian TN, DiBlasio-Smith E, Annis-Freeman B, Marvell TH, LaVallie ER, Zollner RS, Bard J, Somers WS, Stahl ML, Kriz RW.
Bridges KG, et al. Among authors: marvell th.
Peptides. 2006 Jul;27(7):1877-85. doi: 10.1016/j.peptides.2006.02.003. Epub 2006 Mar 30.
Peptides. 2006.
PMID: 16574278
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