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Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.
Buchert M, Athineos D, Abud HE, Burke ZD, Faux MC, Samuel MS, Jarnicki AG, Winbanks CE, Newton IP, Meniel VS, Suzuki H, Stacker SA, Näthke IS, Tosh D, Huelsken J, Clarke AR, Heath JK, Sansom OJ, Ernst M. Buchert M, et al. Among authors: huelsken j. PLoS Genet. 2010 Jan 15;6(1):e1000816. doi: 10.1371/journal.pgen.1000816. PLoS Genet. 2010. PMID: 20084116 Free PMC article.
β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells.
Smartt HJ, Greenhough A, Ordóñez-Morán P, Talero E, Cherry CA, Wallam CA, Parry L, Al Kharusi M, Roberts HR, Mariadason JM, Clarke AR, Huelsken J, Williams AC, Paraskeva C. Smartt HJ, et al. Among authors: huelsken j. Gut. 2012 Sep;61(9):1306-14. doi: 10.1136/gutjnl-2011-300817. Epub 2011 Nov 14. Gut. 2012. PMID: 22082586
66 results