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A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer.
Zhou Q, Gustafson D, Nallapareddy S, Diab S, Leong S, Lewis K, Gore L, Messersmith WA, Treston AM, Eckhardt SG, Sidor C, Camidge DR. Zhou Q, et al. Among authors: messersmith wa. Invest New Drugs. 2011 Apr;29(2):340-6. doi: 10.1007/s10637-009-9383-9. Epub 2010 Jan 19. Invest New Drugs. 2011. PMID: 20084425 Free PMC article. Clinical Trial.
Novel targets in solid tumors: MEK inhibitors.
Messersmith WA, Hidalgo M, Carducci M, Eckhardt SG. Messersmith WA, et al. Clin Adv Hematol Oncol. 2006 Nov;4(11):831-6. Clin Adv Hematol Oncol. 2006. PMID: 17143253 Review.
TNF-blockade in patients with advanced hormone refractory prostate cancer.
Diaz LA Jr, Messersmith W, Sokoll L, Sinibaldi V, Moore S, Carducci M, Eisenberger M. Diaz LA Jr, et al. Invest New Drugs. 2011 Feb;29(1):192-4. doi: 10.1007/s10637-009-9346-1. Epub 2009 Oct 21. Invest New Drugs. 2011. PMID: 19844660 Free PMC article. Clinical Trial. No abstract available.
Thymidylate synthase (TYMS) enhancer region genotype-directed phase II trial of oral capecitabine for 2nd line treatment of advanced pancreatic cancer.
Weekes CD, Nallapareddy S, Rudek MA, Norris-Kirby A, Laheru D, Jimeno A, Donehower RC, Murphy KM, Hidalgo M, Baker SD, Messersmith WA. Weekes CD, et al. Among authors: messersmith wa. Invest New Drugs. 2011 Oct;29(5):1057-65. doi: 10.1007/s10637-010-9413-7. Epub 2010 Mar 23. Invest New Drugs. 2011. PMID: 20306339 Free PMC article. Clinical Trial.
Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer.
Arcaroli JJ, Touban BM, Tan AC, Varella-Garcia M, Powell RW, Eckhardt SG, Elvin P, Gao D, Messersmith WA. Arcaroli JJ, et al. Among authors: messersmith wa. Clin Cancer Res. 2010 Aug 15;16(16):4165-77. doi: 10.1158/1078-0432.CCR-10-0066. Epub 2010 Aug 3. Clin Cancer Res. 2010. PMID: 20682712 Free PMC article.
Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer.
Tentler JJ, Nallapareddy S, Tan AC, Spreafico A, Pitts TM, Morelli MP, Selby HM, Kachaeva MI, Flanigan SA, Kulikowski GN, Leong S, Arcaroli JJ, Messersmith WA, Eckhardt SG. Tentler JJ, et al. Among authors: messersmith wa. Mol Cancer Ther. 2010 Dec;9(12):3351-62. doi: 10.1158/1535-7163.MCT-10-0376. Epub 2010 Oct 5. Mol Cancer Ther. 2010. PMID: 20923857 Free PMC article.
212 results