Rehmann H - Search Results

1

A Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected].

Kortholt A, Bolourani P, Rehmann H, Keizer-Gunnink I, Weeks G, Wittinghofer A, Van Haastert PJ. Kortholt A, et al. Among authors: rehmann h. Mol Biol Cell. 2010 Mar 15;21(6):936-45. doi: 10.1091/mbc.e09-03-0177. Epub 2010 Jan 20. Mol Biol Cell. 2010. PMID: 20089846 Free PMC article.

2

Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum.

Kortholt A, Rehmann H, Kae H, Bosgraaf L, Keizer-Gunnink I, Weeks G, Wittinghofer A, Van Haastert PJ. Kortholt A, et al. Among authors: rehmann h. J Biol Chem. 2006 Aug 18;281(33):23367-76. doi: 10.1074/jbc.M600804200. Epub 2006 Jun 12. J Biol Chem. 2006. PMID: 16769729 Free article.

3

Capturing cyclic nucleotides in action: snapshots from crystallographic studies.

Rehmann H, Wittinghofer A, Bos JL. Rehmann H, et al. Nat Rev Mol Cell Biol. 2007 Jan;8(1):63-73. doi: 10.1038/nrm2082. Nat Rev Mol Cell Biol. 2007. PMID: 17183361 Review.

4

Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs.

Kae H, Kortholt A, Rehmann H, Insall RH, Van Haastert PJ, Spiegelman GB, Weeks G. Kae H, et al. Among authors: rehmann h. EMBO Rep. 2007 May;8(5):477-82. doi: 10.1038/sj.embor.7400936. Epub 2007 Mar 23. EMBO Rep. 2007. PMID: 17380187 Free PMC article.

5

GEFs and GAPs: critical elements in the control of small G proteins.

Bos JL, Rehmann H, Wittinghofer A. Bos JL, et al. Among authors: rehmann h. Cell. 2007 Jun 1;129(5):865-77. doi: 10.1016/j.cell.2007.05.018. Cell. 2007. PMID: 17540168 Free article. Review.

6

Dynamic interaction of cAMP with the Rap guanine-nucleotide exchange factor Epac1.

Kraemer A, Rehmann HR, Cool RH, Theiss C, de Rooij J, Bos JL, Wittinghofer A. Kraemer A, et al. Among authors: rehmann hr. J Mol Biol. 2001 Mar 9;306(5):1167-77. doi: 10.1006/jmbi.2001.4444. J Mol Biol. 2001. PMID: 11237625

7

Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state.

Rehmann H, Das J, Knipscheer P, Wittinghofer A, Bos JL. Rehmann H, et al. Nature. 2006 Feb 2;439(7076):625-8. doi: 10.1038/nature04468. Nature. 2006. PMID: 16452984

8

Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2.

Kuiperij HB, de Rooij J, Rehmann H, van Triest M, Wittinghofer A, Bos JL, Zwartkruis FJ. Kuiperij HB, et al. Among authors: rehmann h. Biochim Biophys Acta. 2003 Feb 17;1593(2-3):141-9. doi: 10.1016/s0167-4889(02)00365-8. Biochim Biophys Acta. 2003. PMID: 12581858 Free article.

9

Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac.

Rehmann H, Rueppel A, Bos JL, Wittinghofer A. Rehmann H, et al. J Biol Chem. 2003 Jun 27;278(26):23508-14. doi: 10.1074/jbc.M301680200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707263 Free article.

Epac is inhibited by an intramolecular interaction between the cAMP-binding domain and the catalytic region in the absence of cAMP. cAMP binding is proposed to induce a conformational change, which allows a LID, an alpha-helix at the C-terminal end of the cAMP-binding site, to co …

Epac is inhibited by an intramolecular interaction between the cAMP-binding domain and the catalytic region in the absence of cAMP. cAMP bin …

10

Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac.

Rehmann H, Schwede F, Døskeland SO, Wittinghofer A, Bos JL. Rehmann H, et al. J Biol Chem. 2003 Oct 3;278(40):38548-56. doi: 10.1074/jbc.M306292200. Epub 2003 Jul 29. J Biol Chem. 2003. PMID: 12888551 Free article.

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