Selkoe DJ - Search Results

1

Aβ oligomers inhibit synapse remodelling necessary for memory consolidation.

Freir DB, Fedriani R, Scully D, Smith IM, Selkoe DJ, Walsh DM, Regan CM. Freir DB, et al. Among authors: selkoe dj. Neurobiol Aging. 2011 Dec;32(12):2211-8. doi: 10.1016/j.neurobiolaging.2010.01.001. Epub 2010 Jan 25. Neurobiol Aging. 2011. PMID: 20097446 Free PMC article.

2

Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.

Podlisny MB, Walsh DM, Amarante P, Ostaszewski BL, Stimson ER, Maggio JE, Teplow DB, Selkoe DJ. Podlisny MB, et al. Among authors: selkoe dj. Biochemistry. 1998 Mar 17;37(11):3602-11. doi: 10.1021/bi972029u. Biochemistry. 1998. PMID: 9521679

3

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates.

Walsh DM, Hartley DM, Kusumoto Y, Fezoui Y, Condron MM, Lomakin A, Benedek GB, Selkoe DJ, Teplow DB. Walsh DM, et al. Among authors: selkoe dj. J Biol Chem. 1999 Sep 3;274(36):25945-52. doi: 10.1074/jbc.274.36.25945. J Biol Chem. 1999. PMID: 10464339 Free article.

4

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

Hartley DM, Walsh DM, Ye CP, Diehl T, Vasquez S, Vassilev PM, Teplow DB, Selkoe DJ. Hartley DM, et al. Among authors: selkoe dj. J Neurosci. 1999 Oct 15;19(20):8876-84. doi: 10.1523/JNEUROSCI.19-20-08876.1999. J Neurosci. 1999. PMID: 10516307 Free PMC article.

5

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain.

Walsh DM, Tseng BP, Rydel RE, Podlisny MB, Selkoe DJ. Walsh DM, et al. Among authors: selkoe dj. Biochemistry. 2000 Sep 5;39(35):10831-9. doi: 10.1021/bi001048s. Biochemistry. 2000. PMID: 10978169

6

In vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's disease.

Walsh DM, Hartley DM, Condron MM, Selkoe DJ, Teplow DB. Walsh DM, et al. Among authors: selkoe dj. Biochem J. 2001 May 1;355(Pt 3):869-77. doi: 10.1042/bj3550869. Biochem J. 2001. PMID: 11311152 Free PMC article.

7

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo.

Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ, Selkoe DJ. Walsh DM, et al. Among authors: selkoe dj. Nature. 2002 Apr 4;416(6880):535-9. doi: 10.1038/416535a. Nature. 2002. PMID: 11932745

8

Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition.

Walsh DM, Klyubin I, Fadeeva JV, Rowan MJ, Selkoe DJ. Walsh DM, et al. Among authors: selkoe dj. Biochem Soc Trans. 2002 Aug;30(4):552-7. doi: 10.1042/bst0300552. Biochem Soc Trans. 2002. PMID: 12196135 Review.

9

The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease.

Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ. Sharon R, et al. Among authors: selkoe dj. Neuron. 2003 Feb 20;37(4):583-95. doi: 10.1016/s0896-6273(03)00024-2. Neuron. 2003. PMID: 12597857 Free article.

10

gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins.

Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ. Walsh DM, et al. Among authors: selkoe dj. Biochemistry. 2003 Jun 10;42(22):6664-73. doi: 10.1021/bi027375c. Biochemistry. 2003. PMID: 12779321

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