Kahle PJ - Search Results

1

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.

Geisler S, Holmström KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W. Geisler S, et al. Among authors: kahle pj. Nat Cell Biol. 2010 Feb;12(2):119-31. doi: 10.1038/ncb2012. Epub 2010 Jan 24. Nat Cell Biol. 2010. PMID: 20098416

2

Mechanisms and models of alpha-synuclein-related neurodegeneration.

Springer W, Kahle PJ. Springer W, et al. Among authors: kahle pj. Curr Neurol Neurosci Rep. 2006 Sep;6(5):432-6. doi: 10.1007/s11910-996-0025-8. Curr Neurol Neurosci Rep. 2006. PMID: 16928354 Review.

3

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.

Exner N, Treske B, Paquet D, Holmström K, Schiesling C, Gispert S, Carballo-Carbajal I, Berg D, Hoepken HH, Gasser T, Krüger R, Winklhofer KF, Vogel F, Reichert AS, Auburger G, Kahle PJ, Schmid B, Haass C. Exner N, et al. Among authors: kahle pj. J Neurosci. 2007 Nov 7;27(45):12413-8. doi: 10.1523/JNEUROSCI.0719-07.2007. J Neurosci. 2007. PMID: 17989306 Free PMC article.

4

Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways.

Hasegawa T, Treis A, Patenge N, Fiesel FC, Springer W, Kahle PJ. Hasegawa T, et al. Among authors: kahle pj. J Neurochem. 2008 Jun;105(5):1700-15. doi: 10.1111/j.1471-4159.2008.05277.x. Epub 2008 Feb 4. J Neurochem. 2008. PMID: 18248610 Free article.

5

Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.

Klein CL, Rovelli G, Springer W, Schall C, Gasser T, Kahle PJ. Klein CL, et al. Among authors: kahle pj. J Neurochem. 2009 Nov;111(3):703-15. doi: 10.1111/j.1471-4159.2009.06358.x. Epub 2009 Aug 27. J Neurochem. 2009. PMID: 19712061 Free article.

6

Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6.

Fiesel FC, Voigt A, Weber SS, Van den Haute C, Waldenmaier A, Görner K, Walter M, Anderson ML, Kern JV, Rasse TM, Schmidt T, Springer W, Kirchner R, Bonin M, Neumann M, Baekelandt V, Alunni-Fabbroni M, Schulz JB, Kahle PJ. Fiesel FC, et al. Among authors: kahle pj. EMBO J. 2010 Jan 6;29(1):209-21. doi: 10.1038/emboj.2009.324. Epub 2009 Nov 12. EMBO J. 2010. PMID: 19910924 Free PMC article.

7

Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.

Kieper N, Holmström KM, Ciceri D, Fiesel FC, Wolburg H, Ziviani E, Whitworth AJ, Martins LM, Kahle PJ, Krüger R. Kieper N, et al. Among authors: kahle pj. Exp Cell Res. 2010 Apr 15;316(7):1213-24. doi: 10.1016/j.yexcr.2010.01.005. Epub 2010 Jan 11. Exp Cell Res. 2010. PMID: 20064504 Free PMC article.

8

Parkinson's disease-associated DJ-1 modulates innate immunity signaling in Caenorhabditis elegans.

Cornejo Castro EM, Waak J, Weber SS, Fiesel FC, Oberhettinger P, Schütz M, Autenrieth IB, Springer W, Kahle PJ. Cornejo Castro EM, et al. Among authors: kahle pj. J Neural Transm (Vienna). 2010 May;117(5):599-604. doi: 10.1007/s00702-010-0397-4. Epub 2010 Apr 8. J Neural Transm (Vienna). 2010. PMID: 20376509

9

The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations.

Geisler S, Holmström KM, Treis A, Skujat D, Weber SS, Fiesel FC, Kahle PJ, Springer W. Geisler S, et al. Among authors: kahle pj. Autophagy. 2010 Oct;6(7):871-8. doi: 10.4161/auto.6.7.13286. Epub 2010 Oct 3. Autophagy. 2010. PMID: 20798600

10

TDP-43-mediated neuron loss in vivo requires RNA-binding activity.

Voigt A, Herholz D, Fiesel FC, Kaur K, Müller D, Karsten P, Weber SS, Kahle PJ, Marquardt T, Schulz JB. Voigt A, et al. Among authors: kahle pj. PLoS One. 2010 Aug 18;5(8):e12247. doi: 10.1371/journal.pone.0012247. PLoS One. 2010. PMID: 20806063 Free PMC article.

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