Lauffenburger DA - Search Results

1

Systems analysis of EGF receptor signaling dynamics with microwestern arrays.

Ciaccio MF, Wagner JP, Chuu CP, Lauffenburger DA, Jones RB. Ciaccio MF, et al. Among authors: lauffenburger da. Nat Methods. 2010 Feb;7(2):148-55. doi: 10.1038/nmeth.1418. Epub 2010 Jan 24. Nat Methods. 2010. PMID: 20101245 Free PMC article.

2

PTMScout, a Web resource for analysis of high throughput post-translational proteomics studies.

Naegle KM, Gymrek M, Joughin BA, Wagner JP, Welsch RE, Yaffe MB, Lauffenburger DA, White FM. Naegle KM, et al. Among authors: lauffenburger da. Mol Cell Proteomics. 2010 Nov;9(11):2558-70. doi: 10.1074/mcp.M110.001206. Epub 2010 Jul 14. Mol Cell Proteomics. 2010. PMID: 20631208 Free PMC article.

3

Signaling network state predicts twist-mediated effects on breast cell migration across diverse growth factor contexts.

Kim HD, Meyer AS, Wagner JP, Alford SK, Wells A, Gertler FB, Lauffenburger DA. Kim HD, et al. Among authors: lauffenburger da. Mol Cell Proteomics. 2011 Nov;10(11):M111.008433. doi: 10.1074/mcp.M111.008433. Epub 2011 Aug 10. Mol Cell Proteomics. 2011. PMID: 21832255 Free PMC article.

4

Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks.

Wagner JP, Wolf-Yadlin A, Sevecka M, Grenier JK, Root DE, Lauffenburger DA, MacBeath G. Wagner JP, et al. Among authors: lauffenburger da. Sci Signal. 2013 Jul 16;6(284):ra58. doi: 10.1126/scisignal.2003994. Sci Signal. 2013. PMID: 23861540 Free PMC article.

5

Engineering epidermal growth factor for enhanced mitogenic potency.

Reddy CC, Niyogi SK, Wells A, Wiley HS, Lauffenburger DA. Reddy CC, et al. Among authors: lauffenburger da. Nat Biotechnol. 1996 Dec;14(13):1696-9. doi: 10.1038/nbt1296-1696. Nat Biotechnol. 1996. PMID: 9634854

6

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data.

Chen WW, Schoeberl B, Jasper PJ, Niepel M, Nielsen UB, Lauffenburger DA, Sorger PK. Chen WW, et al. Among authors: lauffenburger da. Mol Syst Biol. 2009;5:239. doi: 10.1038/msb.2008.74. Epub 2009 Jan 20. Mol Syst Biol. 2009. PMID: 19156131 Free PMC article.

7

Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes.

Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK. Alexopoulos LG, et al. Among authors: lauffenburger da. Mol Cell Proteomics. 2010 Sep;9(9):1849-65. doi: 10.1074/mcp.M110.000406. Epub 2010 May 10. Mol Cell Proteomics. 2010. PMID: 20460255 Free PMC article.

8

Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding.

Kleiman LB, Maiwald T, Conzelmann H, Lauffenburger DA, Sorger PK. Kleiman LB, et al. Among authors: lauffenburger da. Mol Cell. 2011 Sep 2;43(5):723-37. doi: 10.1016/j.molcel.2011.07.014. Mol Cell. 2011. PMID: 21884975 Free PMC article.

9

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.

Hughes SK, Oudin MJ, Tadros J, Neil J, Del Rosario A, Joughin BA, Ritsma L, Wyckoff J, Vasile E, Eddy R, Philippar U, Lussiez A, Condeelis JS, van Rheenen J, White F, Lauffenburger DA, Gertler FB. Hughes SK, et al. Among authors: lauffenburger da. Mol Biol Cell. 2015 Nov 1;26(21):3867-78. doi: 10.1091/mbc.E15-06-0442. Epub 2015 Sep 2. Mol Biol Cell. 2015. PMID: 26337385 Free PMC article.

10

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma.

Randall EC, Emdal KB, Laramy JK, Kim M, Roos A, Calligaris D, Regan MS, Gupta SK, Mladek AC, Carlson BL, Johnson AJ, Lu FK, Xie XS, Joughin BA, Reddy RJ, Peng S, Abdelmoula WM, Jackson PR, Kolluri A, Kellersberger KA, Agar JN, Lauffenburger DA, Swanson KR, Tran NL, Elmquist WF, White FM, Sarkaria JN, Agar NYR. Randall EC, et al. Among authors: lauffenburger da. Nat Commun. 2018 Nov 21;9(1):4904. doi: 10.1038/s41467-018-07334-3. Nat Commun. 2018. PMID: 30464169 Free PMC article.

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