Tomlinson IP - Search Results

1

Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas.

Thirlwell C, Will OC, Domingo E, Graham TA, McDonald SA, Oukrif D, Jeffrey R, Gorman M, Rodriguez-Justo M, Chin-Aleong J, Clark SK, Novelli MR, Jankowski JA, Wright NA, Tomlinson IP, Leedham SJ. Thirlwell C, et al. Among authors: tomlinson ip. Gastroenterology. 2010 Apr;138(4):1441-54, 1454.e1-7. doi: 10.1053/j.gastro.2010.01.033. Epub 2010 Jan 25. Gastroenterology. 2010. PMID: 20102718

2

Polyclonal origin of colonic adenomas in an XO/XY patient with FAP.

Novelli MR, Williamson JA, Tomlinson IP, Elia G, Hodgson SV, Talbot IC, Bodmer WF, Wright NA. Novelli MR, et al. Among authors: tomlinson ip. Science. 1996 May 24;272(5265):1187-90. doi: 10.1126/science.272.5265.1187. Science. 1996. PMID: 8638166

3

Clinico-pathological features and p53 expression in left-sided sporadic colorectal cancers with and without microsatellite instability.

Ilyas M, Tomlinson IP, Novelli MR, Hanby A, Bodmer WF, Talbot IC. Ilyas M, et al. Among authors: tomlinson ip. J Pathol. 1996 Aug;179(4):370-5. doi: 10.1002/(SICI)1096-9896(199608)179:4<370::AID-PATH627>3.0.CO;2-N. J Pathol. 1996. PMID: 8869282

4

The mutation rate and cancer.

Tomlinson IP, Novelli MR, Bodmer WF. Tomlinson IP, et al. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14800-3. doi: 10.1073/pnas.93.25.14800. Proc Natl Acad Sci U S A. 1996. PMID: 8962135 Free PMC article.

5

Tumour recurrence is associated with Jass grouping but not with differences in E-cadherin expression in moderately differentiated Dukes' B colorectal cancers.

Ilyas M, Novelli M, Wilkinson K, Tomlinson IP, Abbasi AM, Forbes A, Talbot IC. Ilyas M, et al. Among authors: tomlinson ip. J Clin Pathol. 1997 Mar;50(3):218-22. doi: 10.1136/jcp.50.3.218. J Clin Pathol. 1997. PMID: 9155672 Free PMC article.

6

Molecular genetics of colon cancer.

Tomlinson I, Ilyas M, Novelli M. Tomlinson I, et al. Cancer Metastasis Rev. 1997 Jun;16(1-2):67-79. doi: 10.1023/a:1005744323215. Cancer Metastasis Rev. 1997. PMID: 9156280 Review.

7

Frequency of germline hereditary non-polyposis colorectal cancer gene mutations in patients with multiple or early onset colorectal adenomas.

Beck NE, Tomlinson IP, Homfray TF, Frayling IM, Hodgson SV, Bodmer WF. Beck NE, et al. Among authors: tomlinson ip. Gut. 1997 Aug;41(2):235-8. doi: 10.1136/gut.41.2.235. Gut. 1997. PMID: 9301504 Free PMC article.

8

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.

Homfray TF, Cottrell SE, Ilyas M, Rowan A, Talbot IC, Bodmer WF, Tomlinson IP. Homfray TF, et al. Among authors: tomlinson ip. Hum Mutat. 1998;11(2):114-20. doi: 10.1002/(SICI)1098-1004(1998)11:2<114::AID-HUMU3>3.0.CO;2-J. Hum Mutat. 1998. PMID: 9482574

9

Inherited susceptibility to colorectal adenomas and carcinomas: evidence for a new predisposition gene on 15q14-q22.

Tomlinson I, Rahman N, Frayling I, Mangion J, Barfoot R, Hamoudi R, Seal S, Northover J, Thomas HJ, Neale K, Hodgson S, Talbot I, Houlston R, Stratton MR. Tomlinson I, et al. Gastroenterology. 1999 Apr;116(4):789-95. doi: 10.1016/s0016-5085(99)70061-2. Gastroenterology. 1999. PMID: 10092300

10

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.

Lamlum H, Ilyas M, Rowan A, Clark S, Johnson V, Bell J, Frayling I, Efstathiou J, Pack K, Payne S, Roylance R, Gorman P, Sheer D, Neale K, Phillips R, Talbot I, Bodmer W, Tomlinson I. Lamlum H, et al. Nat Med. 1999 Sep;5(9):1071-5. doi: 10.1038/12511. Nat Med. 1999. PMID: 10470088

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