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Page 1
Rapid P1 SAR of brain penetrant tertiary carbinamine derived BACE inhibitors.
Zhu H, Young MB, Nantermet PG, Graham SL, Colussi D, Lai MT, Pietrak B, Price EA, Sankaranarayanan S, Shi XP, Tugusheva K, Holahan MA, Michener MS, Cook JJ, Simon A, Hazuda DJ, Vacca JP, Rajapakse HA. Zhu H, et al. Among authors: graham sl. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1779-82. doi: 10.1016/j.bmcl.2010.01.005. Epub 2010 Jan 11. Bioorg Med Chem Lett. 2010. PMID: 20122828
Pseudodipeptide inhibitors of protein farnesyltransferase.
deSolms SJ, Deana AA, Giuliani EA, Graham SL, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Scholz TH, et al. deSolms SJ, et al. Among authors: graham sl. J Med Chem. 1995 Sep 29;38(20):3967-71. doi: 10.1021/jm00020a010. J Med Chem. 1995. PMID: 7562930
Pseudopeptide inhibitors of Ras farnesyl-protein transferase.
Graham SL, deSolms SJ, Giuliani EA, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Breslin MJ, Deana AA, et al. Graham SL, et al. J Med Chem. 1994 Mar 18;37(6):725-32. doi: 10.1021/jm00032a004. J Med Chem. 1994. PMID: 8145221
Sulfonylmethanesulfonamide inhibitors of carbonic anhydrase.
Scholz TH, Sondey JM, Randall WC, Schwam H, Thompson WJ, Mallorga PJ, Sugrue MF, Graham SL. Scholz TH, et al. Among authors: graham sl. J Med Chem. 1993 Jul 23;36(15):2134-41. doi: 10.1021/jm00067a012. J Med Chem. 1993. PMID: 8340917
344 results