Vrang L - Search Results

1

Design and synthesis of potent and selective BACE-1 inhibitors.

Björklund C, Oscarson S, Benkestock K, Borkakoti N, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist A, Samuelsson B. Björklund C, et al. Among authors: vrang l. J Med Chem. 2010 Feb 25;53(4):1458-64. doi: 10.1021/jm901168f. J Med Chem. 2010. PMID: 20128595

2

Design and synthesis of plasmepsin I and plasmepsin II inhibitors with activity in Plasmodium falciparum-infected cultured human erythrocytes.

Nöteberg D, Hamelink E, Hultén J, Wahlgren M, Vrang L, Samuelsson B, Hallberg A. Nöteberg D, et al. Among authors: vrang l. J Med Chem. 2003 Feb 27;46(5):734-46. doi: 10.1021/jm020951i. J Med Chem. 2003. PMID: 12593654

3

Solid-phase library synthesis of reversed-statine type inhibitors of the malarial aspartyl proteases plasmepsin I and II.

Dahlgren A, Kvarnström I, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Dahlgren A, et al. Among authors: vrang l. Bioorg Med Chem. 2003 Mar 20;11(6):827-41. doi: 10.1016/s0968-0896(02)00568-0. Bioorg Med Chem. 2003. PMID: 12614868

4

New potent C2-symmetric malaria plasmepsin I and II inhibitors.

Oscarsson K, Oscarson S, Vrang L, Hamelink E, Hallberg A, Samuelsson B. Oscarsson K, et al. Among authors: vrang l. Bioorg Med Chem. 2003 Apr 3;11(7):1235-46. doi: 10.1016/s0968-0896(02)00643-0. Bioorg Med Chem. 2003. PMID: 12628651

5

New inhibitors of the malaria aspartyl proteases plasmepsin I and II.

Dahlgren A, Kvarnström I, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Dahlgren A, et al. Among authors: vrang l. Bioorg Med Chem. 2003 Aug 5;11(16):3423-37. doi: 10.1016/s0968-0896(03)00312-2. Bioorg Med Chem. 2003. PMID: 12878137

6

Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs.

Johansson PO, Chen Y, Belfrage AK, Blackman MJ, Kvarnström I, Jansson K, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Johansson PO, et al. Among authors: vrang l. J Med Chem. 2004 Jun 17;47(13):3353-66. doi: 10.1021/jm031106i. J Med Chem. 2004. PMID: 15189032

7

Cyclic sulfamide HIV-1 protease inhibitors, with sidechains spanning from P2/P2' to P1/P1'.

Ax A, Schaal W, Vrang L, Samuelsson B, Hallberg A, Karlén A. Ax A, et al. Among authors: vrang l. Bioorg Med Chem. 2005 Feb 1;13(3):755-64. doi: 10.1016/j.bmc.2004.10.042. Bioorg Med Chem. 2005. PMID: 15653343

8

Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II.

Johansson PO, Lindberg J, Blackman MJ, Kvarnström I, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Johansson PO, et al. Among authors: vrang l. J Med Chem. 2005 Jun 30;48(13):4400-9. doi: 10.1021/jm040884n. J Med Chem. 2005. PMID: 15974592

9

High-speed synthesis of potent C2-symmetric HIV-1 protease inhibitors by in-situ aminocarbonylations.

Wannberg J, Kaiser NF, Vrang L, Samuelsson B, Larhed M, Hallberg A. Wannberg J, et al. Among authors: vrang l. J Comb Chem. 2005 Jul-Aug;7(4):611-7. doi: 10.1021/cc050016r. J Comb Chem. 2005. PMID: 16004505

10

Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II.

Muthas D, Nöteberg D, Sabnis YA, Hamelink E, Vrang L, Samuelsson B, Karlén A, Hallberg A. Muthas D, et al. Among authors: vrang l. Bioorg Med Chem. 2005 Sep 15;13(18):5371-90. doi: 10.1016/j.bmc.2005.06.048. Bioorg Med Chem. 2005. PMID: 16054370

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