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P2X7 receptor signaling pathway as a therapeutic target for neurodegenerative diseases.
Takenouchi T, Sekiyama K, Sekigawa A, Fujita M, Waragai M, Sugama S, Iwamaru Y, Kitani H, Hashimoto M. Takenouchi T, et al. Among authors: sekigawa a. Arch Immunol Ther Exp (Warsz). 2010 Apr;58(2):91-6. doi: 10.1007/s00005-010-0069-y. Epub 2010 Feb 9. Arch Immunol Ther Exp (Warsz). 2010. PMID: 20143170 Free article. Review.
The activation of P2X7 receptor induces cathepsin D-dependent production of a 20-kDa form of IL-1β under acidic extracellular pH in LPS-primed microglial cells.
Takenouchi T, Iwamaru Y, Sugama S, Tsukimoto M, Fujita M, Sekigawa A, Sekiyama K, Sato M, Kojima S, Conti B, Hashimoto M, Kitani H. Takenouchi T, et al. Among authors: sekigawa a. J Neurochem. 2011 May;117(4):712-23. doi: 10.1111/j.1471-4159.2011.07240.x. Epub 2011 Mar 28. J Neurochem. 2011. PMID: 21395581 Free article.
19 results