Medvedev A - Search Results

1

Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.

Martin MT, Dix DJ, Judson RS, Kavlock RJ, Reif DM, Richard AM, Rotroff DM, Romanov S, Medvedev A, Poltoratskaya N, Gambarian M, Moeser M, Makarov SS, Houck KA. Martin MT, et al. Among authors: medvedev a. Chem Res Toxicol. 2010 Mar 15;23(3):578-90. doi: 10.1021/tx900325g. Chem Res Toxicol. 2010. PMID: 20143881

2

Homogeneous reporter system enables quantitative functional assessment of multiple transcription factors.

Romanov S, Medvedev A, Gambarian M, Poltoratskaya N, Moeser M, Medvedeva L, Gambarian M, Diatchenko L, Makarov S. Romanov S, et al. Among authors: medvedev a. Nat Methods. 2008 Mar;5(3):253-60. doi: 10.1038/nmeth.1186. Epub 2008 Feb 24. Nat Methods. 2008. PMID: 18297081

3

Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytes.

Tchivileva IE, Tan KS, Gambarian M, Nackley AG, Medvedev AV, Romanov S, Flood PM, Maixner W, Makarov SS, Diatchenko L. Tchivileva IE, et al. Mol Immunol. 2009 Jul;46(11-12):2256-66. doi: 10.1016/j.molimm.2009.04.008. Epub 2009 May 23. Mol Immunol. 2009. PMID: 19477016 Free PMC article.

4

The Identification of Pivotal Transcriptional Factors Mediating Cell Responses to Drugs With Drug-Induced Liver Injury Liabilities.

Shah F, Medvedev A, Wassermann AM, Brodney M, Zhang L, Makarov S, Stanton RV. Shah F, et al. Among authors: medvedev a. Toxicol Sci. 2018 Mar 1;162(1):177-188. doi: 10.1093/toxsci/kfx231. Toxicol Sci. 2018. PMID: 29106686 Free PMC article.

5

Evaluating biological activity of compounds by transcription factor activity profiling.

Medvedev A, Moeser M, Medvedeva L, Martsen E, Granick A, Raines L, Zeng M, Makarov S Jr, Houck KA, Makarov SS. Medvedev A, et al. Sci Adv. 2018 Sep 26;4(9):eaar4666. doi: 10.1126/sciadv.aar4666. eCollection 2018 Sep. Sci Adv. 2018. PMID: 30263952 Free PMC article.

6

Potential Toxicity of Complex Mixtures in Surface Waters from a Nationwide Survey of United States Streams: Identifying in Vitro Bioactivities and Causative Chemicals.

Blackwell BR, Ankley GT, Bradley PM, Houck KA, Makarov SS, Medvedev AV, Swintek J, Villeneuve DL. Blackwell BR, et al. Among authors: medvedev av. Environ Sci Technol. 2019 Jan 15;53(2):973-983. doi: 10.1021/acs.est.8b05304. Epub 2018 Dec 21. Environ Sci Technol. 2019. PMID: 30548063 Free PMC article.

7

Therapeutic suppression of pulmonary neutrophilia and allergic airway hyperresponsiveness by a RORγt inverse agonist.

Whitehead GS, Kang HS, Thomas SY, Medvedev A, Karcz TP, Izumi G, Nakano K, Makarov SS, Nakano H, Jetten AM, Cook DN. Whitehead GS, et al. Among authors: medvedev a. JCI Insight. 2019 Jun 11;5(14):e125528. doi: 10.1172/jci.insight.125528. JCI Insight. 2019. PMID: 31184998 Free PMC article.

8

Harmonized Cross-Species Assessment of Endocrine and Metabolic Disruptors by Ecotox FACTORIAL Assay.

Medvedev AV, Medvedeva LA, Martsen E, Moeser M, Gorman KL, Lin B, Blackwell B, Villeneuve DL, Houck KA, Crofton KM, Makarov SS. Medvedev AV, et al. Environ Sci Technol. 2020 Oct 6;54(19):12142-12153. doi: 10.1021/acs.est.0c03375. Epub 2020 Sep 23. Environ Sci Technol. 2020. PMID: 32901485 Free PMC article.

9

Evaluation of a multiplexed, multispecies nuclear receptor assay for chemical hazard assessment.

Houck KA, Simha A, Bone A, Doering JA, Vliet SMF, LaLone C, Medvedev A, Makarov S. Houck KA, et al. Among authors: medvedev a. Toxicol In Vitro. 2021 Apr;72:105016. doi: 10.1016/j.tiv.2020.105016. Epub 2020 Oct 10. Toxicol In Vitro. 2021. PMID: 33049310 Free PMC article.

10

Bioactivity profiling of per- and polyfluoroalkyl substances (PFAS) identifies potential toxicity pathways related to molecular structure.

Houck KA, Patlewicz G, Richard AM, Williams AJ, Shobair MA, Smeltz M, Clifton MS, Wetmore B, Medvedev A, Makarov S. Houck KA, et al. Among authors: medvedev a. Toxicology. 2021 Jun 15;457:152789. doi: 10.1016/j.tox.2021.152789. Epub 2021 Apr 20. Toxicology. 2021. PMID: 33887376

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