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Absence of adverse effects in cynomolgus macaques treated with CNTO 95, a fully human anti-alphav integrin monoclonal antibody, despite widespread tissue binding.
Martin PL, Jiao Q, Cornacoff J, Hall W, Saville B, Nemeth JA, Schantz A, Mata M, Jang H, Fasanmade AA, Anderson L, Graham MA, Davis HM, Treacy G. Martin PL, et al. Among authors: jiao q. Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6959-65. doi: 10.1158/1078-0432.CCR-04-2623. Clin Cancer Res. 2005. PMID: 16203788
Pharmacokinetics and safety of golimumab, a fully human anti-TNF-alpha monoclonal antibody, in subjects with rheumatoid arthritis.
Zhou H, Jang H, Fleischmann RM, Bouman-Thio E, Xu Z, Marini JC, Pendley C, Jiao Q, Shankar G, Marciniak SJ, Cohen SB, Rahman MU, Baker D, Mascelli MA, Davis HM, Everitt DE. Zhou H, et al. Among authors: jiao q. J Clin Pharmacol. 2007 Mar;47(3):383-96. doi: 10.1177/0091270006298188. J Clin Pharmacol. 2007. PMID: 17322150 Clinical Trial.
A phase I, single and fractionated, ascending-dose study evaluating the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of an erythropoietin mimetic antibody fusion protein (CNTO 528) in healthy male subjects.
Bouman-Thio E, Franson K, Miller B, Getsy J, Cohen A, Bai SA, Yohrling J, Frederick B, Marciniak S, Jiao Q, Jang H, Davis H, Burggraaf J. Bouman-Thio E, et al. Among authors: jiao q. J Clin Pharmacol. 2008 Oct;48(10):1197-207. doi: 10.1177/0091270008322907. J Clin Pharmacol. 2008. PMID: 18812609 Clinical Trial.
Phase I evaluation of a fully human anti-alphav integrin monoclonal antibody (CNTO 95) in patients with advanced solid tumors.
Mullamitha SA, Ton NC, Parker GJ, Jackson A, Julyan PJ, Roberts C, Buonaccorsi GA, Watson Y, Davies K, Cheung S, Hope L, Valle JW, Radford JA, Lawrance J, Saunders MP, Munteanu MC, Nakada MT, Nemeth JA, Davis HM, Jiao Q, Prabhakar U, Lang Z, Corringham RE, Beckman RA, Jayson GC. Mullamitha SA, et al. Among authors: jiao q. Clin Cancer Res. 2007 Apr 1;13(7):2128-35. doi: 10.1158/1078-0432.CCR-06-2779. Clin Cancer Res. 2007. PMID: 17404096 Clinical Trial.
733 results