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Crystal structure of a Legionella pneumophila ecto -triphosphate diphosphohydrolase, a structural and functional homolog of the eukaryotic NTPDases.
Vivian JP, Riedmaier P, Ge H, Le Nours J, Sansom FM, Wilce MC, Byres E, Dias M, Schmidberger JW, Cowan PJ, d'Apice AJ, Hartland EL, Rossjohn J, Beddoe T. Vivian JP, et al. Among authors: hartland el. Structure. 2010 Feb 10;18(2):228-38. doi: 10.1016/j.str.2009.11.014. Structure. 2010. PMID: 20159467 Free article.
A common fold mediates vertebrate defense and bacterial attack.
Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC. Rosado CJ, et al. Among authors: hartland el. Science. 2007 Sep 14;317(5844):1548-51. doi: 10.1126/science.1144706. Epub 2007 Aug 23. Science. 2007. PMID: 17717151
Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence.
Sansom FM, Riedmaier P, Newton HJ, Dunstone MA, Müller CE, Stephan H, Byres E, Beddoe T, Rossjohn J, Cowan PJ, d'Apice AJ, Robson SC, Hartland EL. Sansom FM, et al. Among authors: hartland el. J Biol Chem. 2008 May 9;283(19):12909-18. doi: 10.1074/jbc.M801006200. Epub 2008 Mar 12. J Biol Chem. 2008. PMID: 18337253 Free PMC article.
Significant role for ladC in initiation of Legionella pneumophila infection.
Newton HJ, Sansom FM, Dao J, Cazalet C, Bruggemann H, Albert-Weissenberger C, Buchrieser C, Cianciotto NP, Hartland EL. Newton HJ, et al. Among authors: hartland el. Infect Immun. 2008 Jul;76(7):3075-85. doi: 10.1128/IAI.00209-08. Epub 2008 Apr 21. Infect Immun. 2008. PMID: 18426879 Free PMC article.
Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease.
Cazalet C, Gomez-Valero L, Rusniok C, Lomma M, Dervins-Ravault D, Newton HJ, Sansom FM, Jarraud S, Zidane N, Ma L, Bouchier C, Etienne J, Hartland EL, Buchrieser C. Cazalet C, et al. Among authors: hartland el. PLoS Genet. 2010 Feb 19;6(2):e1000851. doi: 10.1371/journal.pgen.1000851. PLoS Genet. 2010. PMID: 20174605 Free PMC article.
The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication.
Lomma M, Dervins-Ravault D, Rolando M, Nora T, Newton HJ, Sansom FM, Sahr T, Gomez-Valero L, Jules M, Hartland EL, Buchrieser C. Lomma M, et al. Among authors: hartland el. Cell Microbiol. 2010 Sep 1;12(9):1272-91. doi: 10.1111/j.1462-5822.2010.01467.x. Epub 2010 Mar 25. Cell Microbiol. 2010. PMID: 20345489
157 results