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Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation.
Wu HY, Hudry E, Hashimoto T, Kuchibhotla K, Rozkalne A, Fan Z, Spires-Jones T, Xie H, Arbel-Ornath M, Grosskreutz CL, Bacskai BJ, Hyman BT. Wu HY, et al. Among authors: kuchibhotla k. J Neurosci. 2010 Feb 17;30(7):2636-49. doi: 10.1523/JNEUROSCI.4456-09.2010. J Neurosci. 2010. PMID: 20164348 Free PMC article.
Cerebrovascular lesions induce transient β-amyloid deposition.
Garcia-Alloza M, Gregory J, Kuchibhotla KV, Fine S, Wei Y, Ayata C, Frosch MP, Greenberg SM, Bacskai BJ. Garcia-Alloza M, et al. Brain. 2011 Dec;134(Pt 12):3697-707. doi: 10.1093/brain/awr300. Epub 2011 Nov 26. Brain. 2011. PMID: 22120142 Free PMC article.
Opposing Roles of apolipoprotein E in aging and neurodegeneration.
Hudry E, Klickstein J, Cannavo C, Jackson R, Muzikansky A, Gandhi S, Urick D, Sargent T, Wrobleski L, Roe AD, Hou SS, Kuchibhotla KV, Betensky RA, Spires-Jones T, Hyman BT. Hudry E, et al. Life Sci Alliance. 2019 Feb 13;2(1):e201900325. doi: 10.26508/lsa.201900325. Print 2019 Feb. Life Sci Alliance. 2019. PMID: 30760557 Free PMC article.
Abnormal synaptic Ca(2+) homeostasis and morphology in cortical neurons of familial hemiplegic migraine type 1 mutant mice.
Eikermann-Haerter K, Arbel-Ornath M, Yalcin N, Yu ES, Kuchibhotla KV, Yuzawa I, Hudry E, Willard CR, Climov M, Keles F, Belcher AM, Sengul B, Negro A, Rosen IA, Arreguin A, Ferrari MD, van den Maagdenberg AM, Bacskai BJ, Ayata C. Eikermann-Haerter K, et al. Among authors: kuchibhotla kv. Ann Neurol. 2015 Aug;78(2):193-210. doi: 10.1002/ana.24449. Epub 2015 Jul 6. Ann Neurol. 2015. PMID: 26032020 Free PMC article.
29 results