Nyström S - Search Results

1

Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target.

Cummings MD, Lindberg J, Lin TI, de Kock H, Lenz O, Lilja E, Felländer S, Baraznenok V, Nyström S, Nilsson M, Vrang L, Edlund M, Rosenquist A, Samuelsson B, Raboisson P, Simmen K. Cummings MD, et al. Among authors: nystrom s. Angew Chem Int Ed Engl. 2010 Feb 22;49(9):1652-5. doi: 10.1002/anie.200906696. Angew Chem Int Ed Engl. 2010. PMID: 20166108 No abstract available.

2

Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues.

Bäck M, Nyhlén J, Kvarnström I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nyström S, Hallberg A, Rosenquist S, Samuelsson B. Bäck M, et al. Among authors: nystrom s. Bioorg Med Chem. 2008 Nov 1;16(21):9471-86. doi: 10.1016/j.bmc.2008.09.041. Epub 2008 Sep 19. Bioorg Med Chem. 2008. PMID: 18842420

3

Effect of the protonation state of the titratable residues on the inhibitor affinity to BACE-1.

Domínguez JL, Christopeit T, Villaverde MC, Gossas T, Otero JM, Nyström S, Baraznenok V, Lindström E, Danielson UH, Sussman F. Domínguez JL, et al. Among authors: nystrom s. Biochemistry. 2010 Aug 31;49(34):7255-63. doi: 10.1021/bi100637n. Biochemistry. 2010. PMID: 20687525

4

A surface plasmon resonance-based biosensor with full-length BACE1 in a reconstituted membrane.

Christopeit T, Stenberg G, Gossas T, Nyström S, Baraznenok V, Lindström E, Danielson UH. Christopeit T, et al. Among authors: nystrom s. Anal Biochem. 2011 Jul 1;414(1):14-22. doi: 10.1016/j.ab.2011.02.041. Epub 2011 Mar 5. Anal Biochem. 2011. PMID: 21382336

5

Does a fast nuclear magnetic resonance spectroscopy- and X-ray crystallography hybrid approach provide reliable structural information of ligand-protein complexes? A case study of metalloproteinases.

Isaksson J, Nyström S, Derbyshire D, Wallberg H, Agback T, Kovacs H, Bertini I, Giachetti A, Luchinat C. Isaksson J, et al. Among authors: nystrom s. J Med Chem. 2009 Mar 26;52(6):1712-22. doi: 10.1021/jm801388q. J Med Chem. 2009. PMID: 19239231

6

Identification of MMP-12 inhibitors by using biosensor-based screening of a fragment library.

Nordström H, Gossas T, Hämäläinen M, Källblad P, Nyström S, Wallberg H, Danielson UH. Nordström H, et al. Among authors: nystrom s. J Med Chem. 2008 Jun 26;51(12):3449-59. doi: 10.1021/jm8000289. J Med Chem. 2008. PMID: 18494455

7

Membrane protein acylation. Preference for exogenous myristic acid or endogenous saturated chains in Acholeplasma laidlawii.

Nyström S, Wallbrandt P, Wieslander A. Nyström S, et al. Eur J Biochem. 1992 Feb 15;204(1):231-40. doi: 10.1111/j.1432-1033.1992.tb16629.x. Eur J Biochem. 1992. PMID: 1740134 Free article.

8

Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks.

Ismail IH, Nyström S, Nygren J, Hammarsten O. Ismail IH, et al. Among authors: nystrom s. J Biol Chem. 2005 Feb 11;280(6):4649-55. doi: 10.1074/jbc.M411588200. Epub 2004 Nov 15. J Biol Chem. 2005. PMID: 15546858 Free article.

9

Isoprenoid modification of proteins distinct from membrane acyl proteins in the prokaryote Acholeplasma laidlawii.

Nyström S, Wieslander A. Nyström S, et al. Biochim Biophys Acta. 1992 Jun 11;1107(1):39-43. doi: 10.1016/0005-2736(92)90326-h. Biochim Biophys Acta. 1992. PMID: 1616923

10

Selective acylation of membrane proteins in Acholeplasma laidlawii.

Nyström S, Johansson KE, Wieslander A. Nyström S, et al. Eur J Biochem. 1986 Apr 1;156(1):85-94. doi: 10.1111/j.1432-1033.1986.tb09552.x. Eur J Biochem. 1986. PMID: 2420589 Free article.

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