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Stapled peptides with improved potency and specificity that activate p53.
Brown CJ, Quah ST, Jong J, Goh AM, Chiam PC, Khoo KH, Choong ML, Lee MA, Yurlova L, Zolghadr K, Joseph TL, Verma CS, Lane DP. Brown CJ, et al. Among authors: joseph tl. ACS Chem Biol. 2013 Mar 15;8(3):506-12. doi: 10.1021/cb3005148. Epub 2012 Dec 18. ACS Chem Biol. 2013. PMID: 23214419
Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2.
Chee SM, Wongsantichon J, Soo Tng Q, Robinson R, Joseph TL, Verma C, Lane DP, Brown CJ, Ghadessy FJ. Chee SM, et al. Among authors: joseph tl. PLoS One. 2014 Aug 12;9(8):e104914. doi: 10.1371/journal.pone.0104914. eCollection 2014. PLoS One. 2014. PMID: 25115702 Free PMC article.
Inhibition of nutlin-resistant HDM2 mutants by stapled peptides.
Wei SJ, Joseph T, Chee S, Li L, Yurlova L, Zolghadr K, Brown C, Lane D, Verma C, Ghadessy F. Wei SJ, et al. PLoS One. 2013 Nov 20;8(11):e81068. doi: 10.1371/journal.pone.0081068. eCollection 2013. PLoS One. 2013. PMID: 24278380 Free PMC article.
23 results