Keefe DL - Search Results

1

Efficacy, safety and tolerability of aliskiren, a direct renin inhibitor, in women with hypertension: a pooled analysis of eight studies.

Gradman AH, Weir MR, Wright M, Bush CA, Keefe DL. Gradman AH, et al. Among authors: keefe dl. J Hum Hypertens. 2010 Nov;24(11):721-9. doi: 10.1038/jhh.2010.11. Epub 2010 Mar 4. J Hum Hypertens. 2010. PMID: 20200550

2

Long-term safety and tolerability of the oral direct renin inhibitor aliskiren with optional add-on hydrochlorothiazide in patients with hypertension: a randomized, open-label, parallel-group, multicentre, dose-escalation study with an extension phase.

Sica D, Gradman AH, Lederballe O, Kolloch RE, Zhang J, Keefe DL. Sica D, et al. Among authors: keefe dl. Clin Drug Investig. 2011 Dec 1;31(12):825-37. doi: 10.1007/BF03256921. Clin Drug Investig. 2011. PMID: 22035463 Clinical Trial.

3

Antihypertensive efficacy, safety, and tolerability of the oral direct renin inhibitor aliskiren in patients with hypertension: a pooled analysis.

Weir MR, Bush C, Anderson DR, Zhang J, Keefe D, Satlin A. Weir MR, et al. J Am Soc Hypertens. 2007 Jul-Aug;1(4):264-77. doi: 10.1016/j.jash.2007.04.004. J Am Soc Hypertens. 2007. PMID: 20409858

4

Maintenance of blood-pressure-lowering effect following a missed dose of aliskiren, irbesartan or ramipril: results of a randomized, double-blind study.

Palatini P, Jung W, Shlyakhto E, Botha J, Bush C, Keefe DL. Palatini P, et al. Among authors: keefe dl. J Hum Hypertens. 2010 Feb;24(2):93-103. doi: 10.1038/jhh.2009.38. Epub 2009 May 21. J Hum Hypertens. 2010. PMID: 19458624 Clinical Trial.

5

Aliskiren-based therapy lowers blood pressure more effectively than hydrochlorothiazide-based therapy in obese patients with hypertension: sub-analysis of a 52-week, randomized, double-blind trial.

Schmieder RE, Philipp T, Guerediaga J, Gorostidi M, Bush C, Keefe DL. Schmieder RE, et al. Among authors: keefe dl. J Hypertens. 2009 Jul;27(7):1493-501. doi: 10.1097/HJH.0b013e32832be593. J Hypertens. 2009. PMID: 19444142 Clinical Trial.

6

Influence of body weight and gender on the pharmacokinetics, pharmacodynamics, and antihypertensive efficacy of aliskiren.

Jarugula V, Yeh CM, Howard D, Bush C, Keefe DL, Dole WP. Jarugula V, et al. Among authors: keefe dl. J Clin Pharmacol. 2010 Dec;50(12):1358-66. doi: 10.1177/0091270009359525. Epub 2010 Feb 11. J Clin Pharmacol. 2010. PMID: 20150520

7

Aliskiren for geriatric lowering of systolic hypertension: a randomized controlled trial.

Duprez DA, Munger MA, Botha J, Keefe DL, Charney AN. Duprez DA, et al. Among authors: keefe dl. J Hum Hypertens. 2010 Sep;24(9):600-8. doi: 10.1038/jhh.2009.107. Epub 2009 Dec 24. J Hum Hypertens. 2010. PMID: 20033075 Clinical Trial.

8

Comparative efficacy of aliskiren monotherapy and ramipril monotherapy in patients with stage 2 systolic hypertension: subgroup analysis of a double-blind, active comparator trial.

Andersen K, Weinberger MH, Egan B, Constance CM, Wright M, Lukashevich V, Keefe DL. Andersen K, et al. Among authors: keefe dl. Cardiovasc Ther. 2010 Dec;28(6):344-9. doi: 10.1111/j.1755-5922.2010.00148.x. Cardiovasc Ther. 2010. PMID: 20406241 Free article. Clinical Trial.

9

Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trial.

Andersen K, Weinberger MH, Egan B, Constance CM, Ali MA, Jin J, Keefe DL. Andersen K, et al. Among authors: keefe dl. J Hypertens. 2008 Mar;26(3):589-99. doi: 10.1097/HJH.0b013e3282f3ad9a. J Hypertens. 2008. PMID: 18300872 Clinical Trial.

10

Efficacy and safety of aliskiren and amlodipine combination therapy in patients with hypertension: a randomized, double-blind, multifactorial study.

Littlejohn TW 3rd, Jones SW, Zhang J, Hsu H, Keefe DL. Littlejohn TW 3rd, et al. Among authors: keefe dl. J Hum Hypertens. 2013 May;27(5):321-7. doi: 10.1038/jhh.2012.42. Epub 2012 Oct 18. J Hum Hypertens. 2013. PMID: 23076450 Clinical Trial.

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