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Correction to "Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility".
Romero A, Ashcraft L, Chandra A, DiMassa V, Cremin P, Collibee SE, Chuang C, Hartman J, Hwee DT, St Jean D, Malinowski J, DeBenedetto M, Moebius DC, Payette J, Vargas R, Yeoman J, Motani A, Reagan J, Malik FI, Morgan BP. Romero A, et al. Among authors: morgan bp. J Med Chem. 2024 Dec 26. doi: 10.1021/acs.jmedchem.4c02850. Online ahead of print. J Med Chem. 2024. PMID: 39722587 No abstract available.
Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy.
Hartman JJ, Hwee DT, Robert-Paganin J, Chuang C, Chin ER, Edell S, Lee KH, Madhvani R, Paliwal P, Pernier J, Sarkar SS, Schaletzky J, Schauer K, Taheri KD, Wang J, Wehri E, Wu Y, Houdusse A, Morgan BP, Malik FI. Hartman JJ, et al. Among authors: morgan bp. Nat Cardiovasc Res. 2024 Aug;3(8):1003-1016. doi: 10.1038/s44161-024-00505-0. Epub 2024 Jul 23. Nat Cardiovasc Res. 2024. PMID: 39196032 Free PMC article.
535 results