Guy RK - Search Results

1

Synthesis and structure-activity relationships of antimalarial 4-oxo-3-carboxyl quinolones.

Zhang Y, Guiguemde WA, Sigal M, Zhu F, Connelly MC, Nwaka S, Guy RK. Zhang Y, et al. Among authors: guy rk. Bioorg Med Chem. 2010 Apr 1;18(7):2756-66. doi: 10.1016/j.bmc.2010.02.013. Epub 2010 Feb 11. Bioorg Med Chem. 2010. PMID: 20206533 Free PMC article.

2

Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities.

Madrid PB, Sherrill J, Liou AP, Weisman JL, Derisi JL, Guy RK. Madrid PB, et al. Among authors: guy rk. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1015-8. doi: 10.1016/j.bmcl.2004.12.037. Bioorg Med Chem Lett. 2005. PMID: 15686903

3

Parallel synthesis of 9-aminoacridines and their evaluation against chloroquine-resistant Plasmodium falciparum.

Anderson MO, Sherrill J, Madrid PB, Liou AP, Weisman JL, DeRisi JL, Guy RK. Anderson MO, et al. Among authors: guy rk. Bioorg Med Chem. 2006 Jan 15;14(2):334-43. doi: 10.1016/j.bmc.2005.08.017. Epub 2005 Oct 10. Bioorg Med Chem. 2006. PMID: 16216519 Free PMC article.

4

Incorporation of an intramolecular hydrogen-bonding motif in the side chain of 4-aminoquinolines enhances activity against drug-resistant P. falciparum.

Madrid PB, Liou AP, DeRisi JL, Guy RK. Madrid PB, et al. Among authors: guy rk. J Med Chem. 2006 Jul 27;49(15):4535-43. doi: 10.1021/jm0600951. J Med Chem. 2006. PMID: 16854059 Free PMC article.

5

Design of a selective chemical probe for class I PDZ domains.

Fujii N, Shelat A, Hall RA, Guy RK. Fujii N, et al. Among authors: guy rk. Bioorg Med Chem Lett. 2007 Jan 15;17(2):546-8. doi: 10.1016/j.bmcl.2006.10.027. Epub 2006 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17074480

6

Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.

Arnold LA, Kosinski A, Estébanez-Perpiñá E, Fletterick RJ, Guy RK. Arnold LA, et al. Among authors: guy rk. J Med Chem. 2007 Nov 1;50(22):5269-80. doi: 10.1021/jm070556y. Epub 2007 Oct 5. J Med Chem. 2007. PMID: 17918822 Free PMC article.

7

Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

Mallari JP, Shelat AA, Obrien T, Caffrey CR, Kosinski A, Connelly M, Harbut M, Greenbaum D, McKerrow JH, Guy RK. Mallari JP, et al. Among authors: guy rk. J Med Chem. 2008 Feb 14;51(3):545-52. doi: 10.1021/jm070760l. Epub 2008 Jan 4. J Med Chem. 2008. PMID: 18173229

8

A road less traveled by: exploring a decade of Ellman chemistry.

Shelat AA, Guy RK. Shelat AA, et al. Among authors: guy rk. Bioorg Med Chem. 2009 Feb 1;17(3):1088-93. doi: 10.1016/j.bmc.2008.02.087. Epub 2008 Mar 4. Bioorg Med Chem. 2009. PMID: 18343129 Free PMC article.

9

Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB.

Mallari JP, Shelat A, Kosinski A, Caffrey CR, Connelly M, Zhu F, McKerrow JH, Guy RK. Mallari JP, et al. Among authors: guy rk. Bioorg Med Chem Lett. 2008 May 1;18(9):2883-5. doi: 10.1016/j.bmcl.2008.03.083. Epub 2008 Apr 8. Bioorg Med Chem Lett. 2008. PMID: 18420405 Free PMC article.

10

Synthesis and characterization of BODIPY-labeled colchicine.

Arnold LA, Ranaivo P, Guy RK. Arnold LA, et al. Among authors: guy rk. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5867-70. doi: 10.1016/j.bmcl.2008.07.068. Epub 2008 Jul 20. Bioorg Med Chem Lett. 2008. PMID: 18684625 Free PMC article.

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