Hayward NK - Search Results

1

Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244).

Dry JR, Pavey S, Pratilas CA, Harbron C, Runswick S, Hodgson D, Chresta C, McCormack R, Byrne N, Cockerill M, Graham A, Beran G, Cassidy A, Haggerty C, Brown H, Ellison G, Dering J, Taylor BS, Stark M, Bonazzi V, Ravishankar S, Packer L, Xing F, Solit DB, Finn RS, Rosen N, Hayward NK, French T, Smith PD. Dry JR, et al. Among authors: hayward nk. Cancer Res. 2010 Mar 15;70(6):2264-73. doi: 10.1158/0008-5472.CAN-09-1577. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215513 Free PMC article.

2

Microarray expression profiling in melanoma reveals a BRAF mutation signature.

Pavey S, Johansson P, Packer L, Taylor J, Stark M, Pollock PM, Walker GJ, Boyle GM, Harper U, Cozzi SJ, Hansen K, Yudt L, Schmidt C, Hersey P, Ellem KA, O'Rourke MG, Parsons PG, Meltzer P, Ringnér M, Hayward NK. Pavey S, et al. Among authors: hayward nk. Oncogene. 2004 May 20;23(23):4060-7. doi: 10.1038/sj.onc.1207563. Oncogene. 2004. PMID: 15048078

3

Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice.

Hacker E, Muller HK, Irwin N, Gabrielli B, Lincoln D, Pavey S, Powell MB, Malumbres M, Barbacid M, Hayward N, Walker G. Hacker E, et al. Cancer Res. 2006 Mar 15;66(6):2946-52. doi: 10.1158/0008-5472.CAN-05-3196. Cancer Res. 2006. PMID: 16540642

4

Osteopontin is a downstream effector of the PI3-kinase pathway in melanomas that is inversely correlated with functional PTEN.

Packer L, Pavey S, Parker A, Stark M, Johansson P, Clarke B, Pollock P, Ringner M, Hayward N. Packer L, et al. Carcinogenesis. 2006 Sep;27(9):1778-86. doi: 10.1093/carcin/bgl016. Epub 2006 Mar 29. Carcinogenesis. 2006. PMID: 16571650

5

PI3-kinase subunits are infrequent somatic targets in melanoma.

Curtin JA, Stark MS, Pinkel D, Hayward NK, Bastian BC. Curtin JA, et al. Among authors: hayward nk. J Invest Dermatol. 2006 Jul;126(7):1660-3. doi: 10.1038/sj.jid.5700311. Epub 2006 Apr 13. J Invest Dermatol. 2006. PMID: 16614723 Free article. No abstract available.

6

Increased p21-activated kinase-1 expression is associated with invasive potential in uveal melanoma.

Pavey S, Zuidervaart W, van Nieuwpoort F, Packer L, Jager M, Gruis N, Hayward N. Pavey S, et al. Melanoma Res. 2006 Aug;16(4):285-96. doi: 10.1097/01.cmr.0000222589.30117.f2. Melanoma Res. 2006. PMID: 16845324

7

Rapid screening of 4000 individuals for germ-line variations in the BRAF gene.

James MR, Dumeni T, Stark MS, Duffy DL, Montgomery GW, Martin NG, Hayward NK. James MR, et al. Among authors: hayward nk. Clin Chem. 2006 Sep;52(9):1675-8. doi: 10.1373/clinchem.2006.070169. Epub 2006 Jul 27. Clin Chem. 2006. PMID: 16873291

8

Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.

Stark M, Hayward N. Stark M, et al. Cancer Res. 2007 Mar 15;67(6):2632-42. doi: 10.1158/0008-5472.CAN-06-4152. Cancer Res. 2007. PMID: 17363583

9

Gene expression profiling in melanoma identifies novel downstream effectors of p14ARF.

Packer LM, Pavey SJ, Boyle GM, Stark MS, Ayub AL, Rizos H, Hayward NK. Packer LM, et al. Among authors: hayward nk. Int J Cancer. 2007 Aug 15;121(4):784-90. doi: 10.1002/ijc.22725. Int J Cancer. 2007. PMID: 17450523

10

Gene expression signature predicts recurrence in lung adenocarcinoma.

Larsen JE, Pavey SJ, Passmore LH, Bowman RV, Hayward NK, Fong KM. Larsen JE, et al. Among authors: hayward nk. Clin Cancer Res. 2007 May 15;13(10):2946-54. doi: 10.1158/1078-0432.CCR-06-2525. Clin Cancer Res. 2007. PMID: 17504995

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