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Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244).
Dry JR, Pavey S, Pratilas CA, Harbron C, Runswick S, Hodgson D, Chresta C, McCormack R, Byrne N, Cockerill M, Graham A, Beran G, Cassidy A, Haggerty C, Brown H, Ellison G, Dering J, Taylor BS, Stark M, Bonazzi V, Ravishankar S, Packer L, Xing F, Solit DB, Finn RS, Rosen N, Hayward NK, French T, Smith PD. Dry JR, et al. Among authors: xing f. Cancer Res. 2010 Mar 15;70(6):2264-73. doi: 10.1158/0008-5472.CAN-09-1577. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215513 Free PMC article.
Targeting oncogenic BRAF in human cancer.
Pratilas CA, Xing F, Solit DB. Pratilas CA, et al. Among authors: xing f. Curr Top Microbiol Immunol. 2012;355:83-98. doi: 10.1007/82_2011_162. Curr Top Microbiol Immunol. 2012. PMID: 21818706 Free PMC article.
The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner.
Joseph EW, Pratilas CA, Poulikakos PI, Tadi M, Wang W, Taylor BS, Halilovic E, Persaud Y, Xing F, Viale A, Tsai J, Chapman PB, Bollag G, Solit DB, Rosen N. Joseph EW, et al. Among authors: xing f. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14903-8. doi: 10.1073/pnas.1008990107. Epub 2010 Jul 28. Proc Natl Acad Sci U S A. 2010. PMID: 20668238 Free PMC article.
Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF.
Xing F, Persaud Y, Pratilas CA, Taylor BS, Janakiraman M, She QB, Gallardo H, Liu C, Merghoub T, Hefter B, Dolgalev I, Viale A, Heguy A, De Stanchina E, Cobrinik D, Bollag G, Wolchok J, Houghton A, Solit DB. Xing F, et al. Oncogene. 2012 Jan 26;31(4):446-57. doi: 10.1038/onc.2011.250. Epub 2011 Jul 4. Oncogene. 2012. PMID: 21725359 Free PMC article.
Genome-Wide Association Analysis of Growth Traits in Hu Sheep.
Li T, Xing F, Zhang N, Chen J, Zhang Y, Yang H, Peng S, Ma R, Liu Q, Gan S, Wang H. Li T, et al. Among authors: xing f. Genes (Basel). 2024 Dec 20;15(12):1637. doi: 10.3390/genes15121637. Genes (Basel). 2024. PMID: 39766904 Free PMC article.
1,483 results