Shelat AA - Search Results

1

Discovery of potent and selective inhibitors of Trypanosoma brucei ornithine decarboxylase.

Smithson DC, Lee J, Shelat AA, Phillips MA, Guy RK. Smithson DC, et al. Among authors: shelat aa. J Biol Chem. 2010 May 28;285(22):16771-81. doi: 10.1074/jbc.M109.081588. Epub 2010 Mar 10. J Biol Chem. 2010. PMID: 20220141 Free PMC article.

2

Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating.

Yang H, Shelat AA, Guy RK, Gopinath VS, Ma T, Du K, Lukacs GL, Taddei A, Folli C, Pedemonte N, Galietta LJ, Verkman AS. Yang H, et al. Among authors: shelat aa. J Biol Chem. 2003 Sep 12;278(37):35079-85. doi: 10.1074/jbc.M303098200. Epub 2003 Jun 27. J Biol Chem. 2003. PMID: 12832418 Free article.

3

Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain.

Springsteel MF, Galietta LJ, Ma T, By K, Berger GO, Yang H, Dicus CW, Choung W, Quan C, Shelat AA, Guy RK, Verkman AS, Kurth MJ, Nantz MH. Springsteel MF, et al. Among authors: shelat aa. Bioorg Med Chem. 2003 Sep 1;11(18):4113-20. doi: 10.1016/s0968-0896(03)00435-8. Bioorg Med Chem. 2003. PMID: 12927873

4

A solid-phase approach to the phallotoxins: total synthesis of [Ala7]-phalloidin.

Anderson MO, Shelat AA, Guy RK. Anderson MO, et al. Among authors: shelat aa. J Org Chem. 2005 Jun 10;70(12):4578-84. doi: 10.1021/jo0503153. J Org Chem. 2005. PMID: 15932292

5

Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators.

Arnold LA, Estébanez-Perpiñá E, Togashi M, Jouravel N, Shelat A, McReynolds AC, Mar E, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK. Arnold LA, et al. J Biol Chem. 2005 Dec 30;280(52):43048-55. doi: 10.1074/jbc.M506693200. Epub 2005 Oct 31. J Biol Chem. 2005. PMID: 16263725 Free article.

6

A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding.

Arnold LA, Estébanez-Perpiñá E, Togashi M, Shelat A, Ocasio CA, McReynolds AC, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK. Arnold LA, et al. Sci STKE. 2006 Jun 27;2006(341):pl3. doi: 10.1126/stke.3412006pl3. Sci STKE. 2006. PMID: 16804159

7

Searching for new antimalarial therapeutics amongst known drugs.

Weisman JL, Liou AP, Shelat AA, Cohen FE, Guy RK, DeRisi JL. Weisman JL, et al. Among authors: shelat aa. Chem Biol Drug Des. 2006 Jun;67(6):409-16. doi: 10.1111/j.1747-0285.2006.00391.x. Chem Biol Drug Des. 2006. PMID: 16882315 Free PMC article.

8

Design of a selective chemical probe for class I PDZ domains.

Fujii N, Shelat A, Hall RA, Guy RK. Fujii N, et al. Bioorg Med Chem Lett. 2007 Jan 15;17(2):546-8. doi: 10.1016/j.bmcl.2006.10.027. Epub 2006 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17074480

9

The interdependence between screening methods and screening libraries.

Shelat AA, Guy RK. Shelat AA, et al. Curr Opin Chem Biol. 2007 Jun;11(3):244-51. doi: 10.1016/j.cbpa.2007.05.003. Epub 2007 May 23. Curr Opin Chem Biol. 2007. PMID: 17524728 Review.

10

Scaffold composition and biological relevance of screening libraries.

Shelat AA, Guy RK. Shelat AA, et al. Nat Chem Biol. 2007 Aug;3(8):442-6. doi: 10.1038/nchembio0807-442. Nat Chem Biol. 2007. PMID: 17637770

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