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Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus.
Uchida H, Marzulli M, Nakano K, Goins WF, Chan J, Hong CS, Mazzacurati L, Yoo JY, Haseley A, Nakashima H, Baek H, Kwon H, Kumagai I, Kuroki M, Kaur B, Chiocca EA, Grandi P, Cohen JB, Glorioso JC. Uchida H, et al. Among authors: nakashima h. Mol Ther. 2013 Mar;21(3):561-9. doi: 10.1038/mt.2012.211. Epub 2012 Oct 16. Mol Ther. 2013. PMID: 23070115 Free PMC article.
Modification of HSV-1 to an oncolytic virus.
Nakashima H, Chiocca EA. Nakashima H, et al. Methods Mol Biol. 2014;1144:117-27. doi: 10.1007/978-1-4939-0428-0_8. Methods Mol Biol. 2014. PMID: 24671680
Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma.
Nakashima H, Kaufmann JK, Wang PY, Nguyen T, Speranza MC, Kasai K, Okemoto K, Otsuki A, Nakano I, Fernandez S, Goins WF, Grandi P, Glorioso JC, Lawler S, Cripe TP, Chiocca EA. Nakashima H, et al. J Clin Invest. 2015 Nov 2;125(11):4269-80. doi: 10.1172/JCI80713. Epub 2015 Oct 20. J Clin Invest. 2015. PMID: 26524593 Free PMC article.
Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma.
Speranza MC, Passaro C, Ricklefs F, Kasai K, Klein SR, Nakashima H, Kaufmann JK, Ahmed AK, Nowicki MO, Obi P, Bronisz A, Aguilar-Cordova E, Aguilar LK, Guzik BW, Breakefield X, Weissleder R, Freeman GJ, Reardon DA, Wen PY, Chiocca EA, Lawler SE. Speranza MC, et al. Among authors: nakashima h. Neuro Oncol. 2018 Jan 22;20(2):225-235. doi: 10.1093/neuonc/nox139. Neuro Oncol. 2018. PMID: 29016938 Free PMC article.
1,933 results