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Combination treatment with statins and bezafibrate induces myotoxicity via inhibition of geranylgeranyl pyrophosphate biosynthesis and Rho activation in L6 myoblasts and myotube cells.
Tsubaki M, Takeda T, Mastuda T, Kimura A, Yanae M, Maeda A, Hoshida T, Tanabe K, Nishida S. Tsubaki M, et al. Among authors: mastuda t. J Physiol Pharmacol. 2022 Feb;73(1). doi: 10.26402/jpp.2022.1.14. Epub 2022 Jul 4. J Physiol Pharmacol. 2022. PMID: 35793766 Free article.