Kalscheuer R - Search Results

1

Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathway.

Kalscheuer R, Syson K, Veeraraghavan U, Weinrick B, Biermann KE, Liu Z, Sacchettini JC, Besra G, Bornemann S, Jacobs WR Jr. Kalscheuer R, et al. Nat Chem Biol. 2010 May;6(5):376-84. doi: 10.1038/nchembio.340. Epub 2010 Mar 21. Nat Chem Biol. 2010. PMID: 20305657 Free PMC article.

2

Azide-Masked Fluorescence Turn-On Probe for Imaging Mycobacteria.

Liyanage SH, Raviranga NGH, Ryan JG, Shell SS, Ramström O, Kalscheuer R, Yan M. Liyanage SH, et al. Among authors: kalscheuer r. JACS Au. 2023 Mar 27;3(4):1017-1028. doi: 10.1021/jacsau.2c00449. eCollection 2023 Apr 24. JACS Au. 2023. PMID: 37124305 Free PMC article.

3

Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.

Yam KC, D'Angelo I, Kalscheuer R, Zhu H, Wang JX, Snieckus V, Ly LH, Converse PJ, Jacobs WR Jr, Strynadka N, Eltis LD. Yam KC, et al. Among authors: kalscheuer r. PLoS Pathog. 2009 Mar;5(3):e1000344. doi: 10.1371/journal.ppat.1000344. Epub 2009 Mar 20. PLoS Pathog. 2009. PMID: 19300498 Free PMC article.

4

Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids.

Capyk JK, Kalscheuer R, Stewart GR, Liu J, Kwon H, Zhao R, Okamoto S, Jacobs WR Jr, Eltis LD, Mohn WW. Capyk JK, et al. Among authors: kalscheuer r. J Biol Chem. 2009 Dec 18;284(51):35534-42. doi: 10.1074/jbc.M109.072132. J Biol Chem. 2009. PMID: 19846551 Free PMC article.

5

Trehalose-recycling ABC transporter LpqY-SugA-SugB-SugC is essential for virulence of Mycobacterium tuberculosis.

Kalscheuer R, Weinrick B, Veeraraghavan U, Besra GS, Jacobs WR Jr. Kalscheuer R, et al. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21761-6. doi: 10.1073/pnas.1014642108. Epub 2010 Nov 30. Proc Natl Acad Sci U S A. 2010. PMID: 21118978 Free PMC article.

6

The significance of GlgE as a new target for tuberculosis.

Kalscheuer R, Jacobs WR Jr. Kalscheuer R, et al. Drug News Perspect. 2010 Dec;23(10):619-24. doi: 10.1358/dnp.2010.23.10.1534855. Drug News Perspect. 2010. PMID: 21180647 Free article.

7

Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice.

Prados-Rosales R, Baena A, Martinez LR, Luque-Garcia J, Kalscheuer R, Veeraraghavan U, Camara C, Nosanchuk JD, Besra GS, Chen B, Jimenez J, Glatman-Freedman A, Jacobs WR Jr, Porcelli SA, Casadevall A. Prados-Rosales R, et al. Among authors: kalscheuer r. J Clin Invest. 2011 Apr;121(4):1471-83. doi: 10.1172/JCI44261. J Clin Invest. 2011. PMID: 21364279 Free PMC article.

8

Flux through trehalose synthase flows from trehalose to the alpha anomer of maltose in mycobacteria.

Miah F, Koliwer-Brandl H, Rejzek M, Field RA, Kalscheuer R, Bornemann S. Miah F, et al. Among authors: kalscheuer r. Chem Biol. 2013 Apr 18;20(4):487-93. doi: 10.1016/j.chembiol.2013.02.014. Chem Biol. 2013. PMID: 23601637 Free PMC article.

9

Mycobacterium tuberculosis maltosyltransferase GlgE, a genetically validated antituberculosis target, is negatively regulated by Ser/Thr phosphorylation.

Leiba J, Syson K, Baronian G, Zanella-Cléon I, Kalscheuer R, Kremer L, Bornemann S, Molle V. Leiba J, et al. Among authors: kalscheuer r. J Biol Chem. 2013 Jun 7;288(23):16546-16556. doi: 10.1074/jbc.M112.398503. Epub 2013 Apr 22. J Biol Chem. 2013. PMID: 23609448 Free PMC article.

10

Assembly of α-Glucan by GlgE and GlgB in Mycobacteria and Streptomycetes.

Rashid AM, Batey SF, Syson K, Koliwer-Brandl H, Miah F, Barclay JE, Findlay KC, Nartowski KP, Khimyak YZ, Kalscheuer R, Bornemann S. Rashid AM, et al. Among authors: kalscheuer r. Biochemistry. 2016 Jun 14;55(23):3270-84. doi: 10.1021/acs.biochem.6b00209. Epub 2016 Jun 2. Biochemistry. 2016. PMID: 27221142 Free article.

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