Darwish WS - Search Results

1

Metabolic activation of heterocyclic amines and expression of CYP1A1 in the tongue.

Takiguchi M, Darwish WS, Ikenaka Y, Ohno M, Ishizuka M. Takiguchi M, et al. Among authors: darwish ws. Toxicol Sci. 2010 Jul;116(1):79-91. doi: 10.1093/toxsci/kfq087. Epub 2010 Mar 22. Toxicol Sci. 2010. PMID: 20308224 Free article.

2

Carotenoids as regulators for inter-species difference in cytochrome P450 1A expression and activity in ungulates and rats.

Darwish WS, Ikenaka Y, Ohno M, Eldaly EA, Ishizuka M. Darwish WS, et al. Food Chem Toxicol. 2010 Nov;48(11):3201-8. doi: 10.1016/j.fct.2010.08.022. Epub 2010 Aug 24. Food Chem Toxicol. 2010. PMID: 20797421 Free article.

3

Metabolic Activation of Heterocyclic Amines and Expression of Xenobiotic-Metabolizing Enzymes in the Gastrointestinal Tract of Rats.

Darwish WS, Nakayama SM, Itotani Y, Ohno M, Ikenaka Y, Ishizuka M. Darwish WS, et al. J Food Sci. 2015 Jul;80(7):T1627-32. doi: 10.1111/1750-3841.12931. Epub 2015 Jun 16. J Food Sci. 2015. PMID: 26081582

4

Cytochrome P450-mediated warfarin metabolic ability is not a critical determinant of warfarin sensitivity in avian species: In vitro assays in several birds and in vivo assays in chicken.

Watanabe KP, Kawata M, Ikenaka Y, Nakayama SM, Ishii C, Darwish WS, Saengtienchai A, Mizukawa H, Ishizuka M. Watanabe KP, et al. Among authors: darwish ws. Environ Toxicol Chem. 2015 Oct;34(10):2328-34. doi: 10.1002/etc.3062. Epub 2015 Aug 27. Environ Toxicol Chem. 2015. PMID: 25959534 Free article.

5

High expression of the mRNA of cytochrome P450 and phase II enzymes in the lung and kidney tissues of cattle.

Darwish WS, Ikenaka Y, El-Ghareeb WR, Ishizuka M. Darwish WS, et al. Animal. 2010 Dec;4(12):2023-9. doi: 10.1017/S1751731110001394. Animal. 2010. PMID: 22445377 Free article.

6

Mutagenic activation and detoxification of benzo[a]pyrene in vitro by hepatic cytochrome P450 1A1 and phase II enzymes in three meat-producing animals.

Darwish W, Ikenaka Y, Eldaly E, Ishizuka M. Darwish W, et al. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2526-31. doi: 10.1016/j.fct.2010.06.026. Epub 2010 Jun 18. Food Chem Toxicol. 2010. PMID: 20600538 Free article.

7

Astaxanthin can alter CYP1A-dependent activities via two different mechanisms: induction of protein expression and inhibition of NADPH P450 reductase dependent electron transfer.

Ohno M, Darwish WS, Ikenaka Y, Miki W, Ishizuka M. Ohno M, et al. Among authors: darwish ws. Food Chem Toxicol. 2011 Jun;49(6):1285-91. doi: 10.1016/j.fct.2011.03.009. Epub 2011 Mar 23. Food Chem Toxicol. 2011. PMID: 21414371 Free article.

8

Constitutive Effects of Lead on Aryl Hydrocarbon Receptor Gene Battery and Protection by β-carotene and Ascorbic Acid in Human HepG2 Cells.

Darwish WS, Ikenaka Y, Nakayama SM, Mizukawa H, Ishizuka M. Darwish WS, et al. J Food Sci. 2016 Jan;81(1):T275-81. doi: 10.1111/1750-3841.13162. Epub 2015 Dec 2. J Food Sci. 2016. PMID: 26630500

9

Molecular evaluation of a new highly sensitive aryl hydrocarbon receptor in ostriches.

Fujisawa N, Darwish WS, Ikenaka Y, Kim E, Lee J, Iwata H, Nakayama S, Ishizuka M. Fujisawa N, et al. Among authors: darwish ws. Poult Sci. 2013 Jul;92(7):1921-9. doi: 10.3382/ps.2013-03090. Poult Sci. 2013. PMID: 23776281 Free article.

10

Characterization of equine cytochrome P450: role of CYP3A in the metabolism of diazepam.

Nakayama SM, Ikenaka Y, Hayami A, Mizukawa H, Darwish WS, Watanabe KP, Kawai YK, Ishizuka M. Nakayama SM, et al. Among authors: darwish ws. J Vet Pharmacol Ther. 2016 Oct;39(5):478-87. doi: 10.1111/jvp.12303. Epub 2016 Mar 11. J Vet Pharmacol Ther. 2016. PMID: 26970544

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