Chan CT - Search Results

1

Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.

Fu D, Brophy JA, Chan CT, Atmore KA, Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD. Fu D, et al. Among authors: chan ct. Mol Cell Biol. 2010 May;30(10):2449-59. doi: 10.1128/MCB.01604-09. Epub 2010 Mar 22. Mol Cell Biol. 2010. PMID: 20308323 Free PMC article.

2

A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.

Chan CT, Dyavaiah M, DeMott MS, Taghizadeh K, Dedon PC, Begley TJ. Chan CT, et al. PLoS Genet. 2010 Dec 16;6(12):e1001247. doi: 10.1371/journal.pgen.1001247. PLoS Genet. 2010. PMID: 21187895 Free PMC article.

3

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins.

Chan CT, Pang YL, Deng W, Babu IR, Dyavaiah M, Begley TJ, Dedon PC. Chan CT, et al. Nat Commun. 2012 Jul 3;3:937. doi: 10.1038/ncomms1938. Nat Commun. 2012. PMID: 22760636 Free PMC article.

4

Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response.

Patil A, Dyavaiah M, Joseph F, Rooney JP, Chan CT, Dedon PC, Begley TJ. Patil A, et al. Among authors: chan ct. Cell Cycle. 2012 Oct 1;11(19):3656-65. doi: 10.4161/cc.21919. Epub 2012 Aug 30. Cell Cycle. 2012. PMID: 22935709 Free PMC article.

5

A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α.

Begley U, Sosa MS, Avivar-Valderas A, Patil A, Endres L, Estrada Y, Chan CT, Su D, Dedon PC, Aguirre-Ghiso JA, Begley T. Begley U, et al. Among authors: chan ct. EMBO Mol Med. 2013 Mar;5(3):366-83. doi: 10.1002/emmm.201201161. Epub 2013 Feb 4. EMBO Mol Med. 2013. PMID: 23381944 Free PMC article.

6

Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry.

Su D, Chan CT, Gu C, Lim KS, Chionh YH, McBee ME, Russell BS, Babu IR, Begley TJ, Dedon PC. Su D, et al. Among authors: chan ct. Nat Protoc. 2014 Apr;9(4):828-41. doi: 10.1038/nprot.2014.047. Epub 2014 Mar 13. Nat Protoc. 2014. PMID: 24625781 Free PMC article.

7

Identification of N6,N6-dimethyladenosine in transfer RNA from Mycobacterium bovis Bacille Calmette-Guérin.

Chan CT, Chionh YH, Ho CH, Lim KS, Babu IR, Ang E, Wenwei L, Alonso S, Dedon PC. Chan CT, et al. Molecules. 2011 Jun 21;16(6):5168-81. doi: 10.3390/molecules16065168. Molecules. 2011. PMID: 21694680 Free PMC article.

8

Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications.

Patil A, Chan CT, Dyavaiah M, Rooney JP, Dedon PC, Begley TJ. Patil A, et al. Among authors: chan ct. RNA Biol. 2012 Jul;9(7):990-1001. doi: 10.4161/rna.20531. Epub 2012 Jul 1. RNA Biol. 2012. PMID: 22832247 Free PMC article.

9

Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes.

Chan CT, Deng W, Li F, DeMott MS, Babu IR, Begley TJ, Dedon PC. Chan CT, et al. Chem Res Toxicol. 2015 May 18;28(5):978-88. doi: 10.1021/acs.chemrestox.5b00004. Epub 2015 Apr 13. Chem Res Toxicol. 2015. PMID: 25772370 Free PMC article.

10

Identification and codon reading properties of 5-cyanomethyl uridine, a new modified nucleoside found in the anticodon wobble position of mutant haloarchaeal isoleucine tRNAs.

Mandal D, Köhrer C, Su D, Babu IR, Chan CT, Liu Y, Söll D, Blum P, Kuwahara M, Dedon PC, Rajbhandary UL. Mandal D, et al. Among authors: chan ct. RNA. 2014 Feb;20(2):177-88. doi: 10.1261/rna.042358.113. Epub 2013 Dec 16. RNA. 2014. PMID: 24344322 Free PMC article.

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