Coppola D - Search Results

1

Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation.

Mahajan K, Coppola D, Challa S, Fang B, Chen YA, Zhu W, Lopez AS, Koomen J, Engelman RW, Rivera C, Muraoka-Cook RS, Cheng JQ, Schönbrunn E, Sebti SM, Earp HS, Mahajan NP. Mahajan K, et al. Among authors: coppola d. PLoS One. 2010 Mar 19;5(3):e9646. doi: 10.1371/journal.pone.0009646. PLoS One. 2010. PMID: 20333297 Free PMC article.

2

The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis.

Jiang K, Coppola D, Crespo NC, Nicosia SV, Hamilton AD, Sebti SM, Cheng JQ. Jiang K, et al. Among authors: coppola d. Mol Cell Biol. 2000 Jan;20(1):139-48. doi: 10.1128/MCB.20.1.139-148.2000. Mol Cell Biol. 2000. PMID: 10594016 Free PMC article.

3

Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer.

Yuan ZQ, Sun M, Feldman RI, Wang G, Ma X, Jiang C, Coppola D, Nicosia SV, Cheng JQ. Yuan ZQ, et al. Among authors: coppola d. Oncogene. 2000 May 4;19(19):2324-30. doi: 10.1038/sj.onc.1203598. Oncogene. 2000. PMID: 10822383

4

Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice.

Blaskovich MA, Lin Q, Delarue FL, Sun J, Park HS, Coppola D, Hamilton AD, Sebti SM. Blaskovich MA, et al. Among authors: coppola d. Nat Biotechnol. 2000 Oct;18(10):1065-70. doi: 10.1038/80257. Nat Biotechnol. 2000. PMID: 11017044

5

Retinoblastoma protein activation of interleukin 8 expression inhibits tumor cell survival in nude mice.

Zhang H, Wei S, Sun J, Coppola D, Zhong B, Wu GD, Goodwin B, Sebti S, Djeu JY, Blanck G. Zhang H, et al. Among authors: coppola d. Cell Growth Differ. 2000 Dec;11(12):635-9. Cell Growth Differ. 2000. PMID: 11149598

6

CEP1612, a dipeptidyl proteasome inhibitor, induces p21WAF1 and p27KIP1 expression and apoptosis and inhibits the growth of the human lung adenocarcinoma A-549 in nude mice.

Sun J, Nam S, Lee CS, Li B, Coppola D, Hamilton AD, Dou QP, Sebti SM. Sun J, et al. Among authors: coppola d. Cancer Res. 2001 Feb 15;61(4):1280-4. Cancer Res. 2001. PMID: 11245420

7

Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.

Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, Lu YY, Shelley SA, Nicosia SV, Cheng JQ. Sun M, et al. Among authors: coppola d. Cancer Res. 2001 Aug 15;61(16):5985-91. Cancer Res. 2001. PMID: 11507039

8

Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells.

Yuan ZQ, Feldman RI, Sun M, Olashaw NE, Coppola D, Sussman GE, Shelley SA, Nicosia SV, Cheng JQ. Yuan ZQ, et al. Among authors: coppola d. J Biol Chem. 2002 Aug 16;277(33):29973-82. doi: 10.1074/jbc.M203636200. Epub 2002 Jun 4. J Biol Chem. 2002. Retraction in: J Biol Chem. 2016 Oct 21;291(43):22849. doi: 10.1074/jbc.A116.203636. PMID: 12048203 Free article. Retracted.

9

Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models.

Jackson RJ, Adnane J, Coppola D, Cantor A, Sebti SM, Pledger WJ. Jackson RJ, et al. Among authors: coppola d. Oncogene. 2002 Dec 5;21(55):8486-97. doi: 10.1038/sj.onc.1205946. Oncogene. 2002. PMID: 12466968

10

Combination therapy with AG-490 and interleukin 12 achieves greater antitumor effects than either agent alone.

Burdelya L, Catlett-Falcone R, Levitzki A, Cheng F, Mora LB, Sotomayor E, Coppola D, Sun J, Sebti S, Dalton WS, Jove R, Yu H. Burdelya L, et al. Among authors: coppola d. Mol Cancer Ther. 2002 Sep;1(11):893-9. Mol Cancer Ther. 2002. PMID: 12481410

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