Carvalho I - Search Results

1

'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase.

Carvalho I, Andrade P, Campo VL, Guedes PM, Sesti-Costa R, Silva JS, Schenkman S, Dedola S, Hill L, Rejzek M, Nepogodiev SA, Field RA. Carvalho I, et al. Bioorg Med Chem. 2010 Apr 1;18(7):2412-27. doi: 10.1016/j.bmc.2010.02.053. Epub 2010 Mar 2. Bioorg Med Chem. 2010. PMID: 20335038 Free article.

2

Practical synthesis of the 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D-glucosides of Fmoc-serine and Fmoc-threonine and their benzyl esters.

Carvalho I, Scheuerl SL, Ravindranathan Kartha KP, Field RA. Carvalho I, et al. Carbohydr Res. 2003 May 1;338(10):1039-43. doi: 10.1016/s0008-6215(03)00071-5. Carbohydr Res. 2003. PMID: 12706969

3

Molecular modeling, docking and ADMET studies applied to the design of a novel hybrid for treatment of Alzheimer's disease.

da Silva CH, Campo VL, Carvalho I, Taft CA. da Silva CH, et al. Among authors: carvalho i. J Mol Graph Model. 2006 Oct;25(2):169-75. doi: 10.1016/j.jmgm.2005.12.002. Epub 2006 Jan 18. J Mol Graph Model. 2006. PMID: 16413803

4

Synthesis and trypanocidal activity of 1,4-bis-(3,4,5-trimethoxy-phenyl)-1,4-butanediol and 1,4-bis-(3,4-dimethoxyphenyl)-1,4-butanediol.

Bernardes LS, Kato MJ, Albuquerque S, Carvalho I. Bernardes LS, et al. Among authors: carvalho i. Bioorg Med Chem. 2006 Nov 1;14(21):7075-82. doi: 10.1016/j.bmc.2006.07.006. Bioorg Med Chem. 2006. PMID: 16908164

5

Aminoglycoside antibiotic derivatives: preparation and evaluation of toxicity on cochlea and vestibular tissues and antimicrobial activity.

da Silva JG, Hyppolito MA, de Oliveira JA, Corrado AP, Ito IY, Carvalho I. da Silva JG, et al. Among authors: carvalho i. Bioorg Med Chem. 2007 Jun 1;15(11):3624-34. doi: 10.1016/j.bmc.2007.03.056. Epub 2007 Mar 23. Bioorg Med Chem. 2007. PMID: 17416529

6

New insights into aminoglycoside antibiotics and derivatives.

Silva JG, Carvalho I. Silva JG, et al. Among authors: carvalho i. Curr Med Chem. 2007;14(10):1101-19. doi: 10.2174/092986707780362817. Curr Med Chem. 2007. PMID: 17456024 Review.

7

Chemical and chemoenzymatic synthesis of glycosyl-amino acids and glycopeptides related to Trypanosoma cruzi mucins.

Campo VL, Carvalho I, Allman S, Davis BG, Field RA. Campo VL, et al. Among authors: carvalho i. Org Biomol Chem. 2007 Aug 21;5(16):2645-57. doi: 10.1039/b707772f. Org Biomol Chem. 2007. PMID: 18019540

8

Stereoselectivity in drug metabolism: molecular mechanisms and analytical methods.

Campo VL, Bernardes LS, Carvalho I. Campo VL, et al. Among authors: carvalho i. Curr Drug Metab. 2009 Feb;10(2):188-205. doi: 10.2174/138920009787522188. Curr Drug Metab. 2009. PMID: 19275553 Review.

9

Design, synthesis and the effect of 1,2,3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase.

Campo VL, Sesti-Costa R, Carneiro ZA, Silva JS, Schenkman S, Carvalho I. Campo VL, et al. Among authors: carvalho i. Bioorg Med Chem. 2012 Jan 1;20(1):145-56. doi: 10.1016/j.bmc.2011.11.022. Epub 2011 Nov 22. Bioorg Med Chem. 2012. PMID: 22154559 Free article.

10

Novel aryl β-aminocarbonyl derivatives as inhibitors of Trypanosoma cruzi trypanothione reductase: binding mode revised by docking and GRIND2-based 3D-QSAR procedures.

de Paula da Silva CH, Bernardes LS, da Silva VB, Zani CL, Carvalho I. de Paula da Silva CH, et al. Among authors: carvalho i. J Biomol Struct Dyn. 2012;29(6):702-16. doi: 10.1080/07391102.2011.672633. J Biomol Struct Dyn. 2012. PMID: 22546000

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