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Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.
Klaiber M, Kruse M, Völker K, Schröter J, Feil R, Freichel M, Gerling A, Feil S, Dietrich A, Londoño JE, Baba HA, Abramowitz J, Birnbaumer L, Penninger JM, Pongs O, Kuhn M. Klaiber M, et al. Among authors: freichel m. Basic Res Cardiol. 2010 Sep;105(5):583-95. doi: 10.1007/s00395-010-0098-z. Epub 2010 Mar 30. Basic Res Cardiol. 2010. PMID: 20352235 Free PMC article.
MASTER-NAADP: a membrane permeable precursor of the Ca2+ mobilizing second messenger NAADP.
Krukenberg S, Möckl F, Weiß M, Dekiert P, Hofmann M, Gerlach F, Winterberg KJ, Kovacevic D, Khansahib I, Troost B, Hinrichs M, Granato V, Nawrocki M, Hub T, Tsvilovskyy V, Medert R, Woelk LM, Förster F, Li H, Werner R, Altfeld M, Huber S, Clarke OB, Freichel M, Diercks BP, Meier C, Guse AH. Krukenberg S, et al. Among authors: freichel m. Nat Commun. 2024 Sep 13;15(1):8008. doi: 10.1038/s41467-024-52024-y. Nat Commun. 2024. PMID: 39271671 Free PMC article.
Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells.
Woo MS, Ufer F, Sonner JK, Belkacemi A, Tintelnot J, Sáez PJ, Krieg PF, Mayer C, Binkle-Ladisch L, Engler JB, Bauer S, Kursawe N, Vieira V, Mannebach S, Freichel M, Flockerzi V, Vargas P, Friese MA. Woo MS, et al. Among authors: freichel m. Sci Adv. 2023 Sep 22;9(38):eadh1653. doi: 10.1126/sciadv.adh1653. Epub 2023 Sep 20. Sci Adv. 2023. PMID: 37729408 Free PMC article.
Knock-Out of IKKepsilon Ameliorates Atherosclerosis and Fatty Liver Disease by Alterations of Lipid Metabolism in the PCSK9 Model in Mice.
Weiss U, Mungo E, Haß M, Benning D, Gurke R, Hahnefeld L, Dorochow E, Schlaudraff J, Schmid T, Kuntschar S, Meyer S, Medert R, Freichel M, Geisslinger G, Niederberger E. Weiss U, et al. Among authors: freichel m. Int J Mol Sci. 2024 Oct 5;25(19):10721. doi: 10.3390/ijms251910721. Int J Mol Sci. 2024. PMID: 39409049 Free PMC article.
TRPC3 channels are required for synaptic transmission and motor coordination.
Hartmann J, Dragicevic E, Adelsberger H, Henning HA, Sumser M, Abramowitz J, Blum R, Dietrich A, Freichel M, Flockerzi V, Birnbaumer L, Konnerth A. Hartmann J, et al. Among authors: freichel m. Neuron. 2008 Aug 14;59(3):392-8. doi: 10.1016/j.neuron.2008.06.009. Neuron. 2008. PMID: 18701065 Free PMC article.
A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide.
Klaiber M, Dankworth B, Kruse M, Hartmann M, Nikolaev VO, Yang RB, Völker K, Gassner B, Oberwinkler H, Feil R, Freichel M, Groschner K, Skryabin BV, Frantz S, Birnbaumer L, Pongs O, Kuhn M. Klaiber M, et al. Among authors: freichel m. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18500-5. doi: 10.1073/pnas.1103300108. Epub 2011 Oct 25. Proc Natl Acad Sci U S A. 2011. PMID: 22027011 Free PMC article.
Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration.
Phelan KD, Mock MM, Kretz O, Shwe UT, Kozhemyakin M, Greenfield LJ, Dietrich A, Birnbaumer L, Freichel M, Flockerzi V, Zheng F. Phelan KD, et al. Among authors: freichel m. Mol Pharmacol. 2012 Mar;81(3):384-92. doi: 10.1124/mol.111.075341. Epub 2011 Dec 5. Mol Pharmacol. 2012. PMID: 22144671 Free PMC article.
155 results