Hochalter JB - Search Results

1

Analysis of phenanthrene and benzo[a]pyrene tetraol enantiomers in human urine: relevance to the bay region diol epoxide hypothesis of benzo[a]pyrene carcinogenesis and to biomarker studies.

Hecht SS, Carmella SG, Villalta PW, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Chem Res Toxicol. 2010 May 17;23(5):900-8. doi: 10.1021/tx9004538. Chem Res Toxicol. 2010. PMID: 20369855 Free PMC article.

2

Quantitation of enantiomers of r-7,t-8,9,c-10-tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]-pyrene in human urine: evidence supporting metabolic activation of benzo[a]pyrene via the bay region diol epoxide.

Hecht SS, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Mutagenesis. 2014 Sep;29(5):351-6. doi: 10.1093/mutage/geu024. Epub 2014 Jul 21. Mutagenesis. 2014. PMID: 25053834 Free PMC article.

3

Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosine.

Wang M, Yu N, Chen L, Villalta PW, Hochalter JB, Hecht SS. Wang M, et al. Among authors: hochalter jb. Chem Res Toxicol. 2006 Feb;19(2):319-24. doi: 10.1021/tx0502948. Chem Res Toxicol. 2006. PMID: 16485909 Free PMC article.

4

Quantitation of N-acetyl-S-(9,10-dihydro-9-hydroxy-10-phenanthryl)-L-cysteine in human urine: comparison with glutathione-S-transferase genotypes in smokers.

Upadhyaya P, Rao P, Hochalter JB, Li ZZ, Villalta PW, Hecht SS. Upadhyaya P, et al. Among authors: hochalter jb. Chem Res Toxicol. 2006 Sep;19(9):1234-40. doi: 10.1021/tx060096w. Chem Res Toxicol. 2006. PMID: 16978029 Free PMC article.

5

Investigation of the reaction of myosmine with sodium nitrite in vitro and in rats.

Hecht SS, Han S, Kenney PM, Wang M, Lindgren B, Wang Y, Lao Y, Hochalter JB, Upadhyaya P. Hecht SS, et al. Among authors: hochalter jb. Chem Res Toxicol. 2007 Mar;20(3):543-9. doi: 10.1021/tx600328e. Epub 2007 Feb 10. Chem Res Toxicol. 2007. PMID: 17291014 Free PMC article.

6

Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphisms.

Hecht SS, Villalta PW, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Carcinogenesis. 2008 May;29(5):937-43. doi: 10.1093/carcin/bgn015. Epub 2008 May 13. Carcinogenesis. 2008. PMID: 18477646 Free PMC article.

7

Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Upadhyaya P, Kalscheuer S, Hochalter JB, Villalta PW, Hecht SS. Upadhyaya P, et al. Among authors: hochalter jb. Chem Res Toxicol. 2008 Jul;21(7):1468-76. doi: 10.1021/tx8001109. Epub 2008 Jun 21. Chem Res Toxicol. 2008. PMID: 18570389 Free PMC article.

8

Preferential glutathione conjugation of a reverse diol epoxide compared to a bay region diol epoxide of phenanthrene in human hepatocytes: relevance to molecular epidemiology studies of glutathione-s-transferase polymorphisms and cancer.

Hecht SS, Berg JZ, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Chem Res Toxicol. 2009 Mar 16;22(3):426-32. doi: 10.1021/tx800315m. Chem Res Toxicol. 2009. PMID: 19187038 Free PMC article.

9

Preferential glutathione conjugation of a reverse diol epoxide compared with a bay region diol epoxide of benzo[a]pyrene in human hepatocytes.

Upadhyaya P, Hochalter JB, Balbo S, McIntee EJ, Hecht SS. Upadhyaya P, et al. Among authors: hochalter jb. Drug Metab Dispos. 2010 Sep;38(9):1397-402. doi: 10.1124/dmd.110.034181. Epub 2010 Jun 14. Drug Metab Dispos. 2010. PMID: 20547966 Free PMC article.

10

Analysis of r-7,t-8,9,c-10-tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene in human urine: a biomarker for directly assessing carcinogenic polycyclic aromatic hydrocarbon exposure plus metabolic activation.

Zhong Y, Carmella SG, Hochalter JB, Balbo S, Hecht SS. Zhong Y, et al. Among authors: hochalter jb. Chem Res Toxicol. 2011 Jan 14;24(1):73-80. doi: 10.1021/tx100287n. Epub 2010 Nov 4. Chem Res Toxicol. 2011. PMID: 21049951 Free PMC article.

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