Copple IM - Search Results

1

Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway.

Copple IM, Lister A, Obeng AD, Kitteringham NR, Jenkins RE, Layfield R, Foster BJ, Goldring CE, Park BK. Copple IM, et al. J Biol Chem. 2010 May 28;285(22):16782-8. doi: 10.1074/jbc.M109.096545. Epub 2010 Apr 8. J Biol Chem. 2010. PMID: 20378532 Free PMC article.

2

Plasticity in cell defence: access to and reactivity of critical protein residues and DNA response elements.

Goldring C, Kitteringham N, Jenkins R, Copple I, Jeannin JF, Park BK. Goldring C, et al. J Exp Biol. 2006 Jun;209(Pt 12):2337-43. doi: 10.1242/jeb.02209. J Exp Biol. 2006. PMID: 16731810 Review.

3

Extract of Ginkgo biloba induces phase 2 genes through Keap1-Nrf2-ARE signaling pathway.

Liu XP, Goldring CE, Copple IM, Wang HY, Wei W, Kitteringham NR, Park BK. Liu XP, et al. Among authors: copple im. Life Sci. 2007 Apr 3;80(17):1586-91. doi: 10.1016/j.lfs.2007.01.034. Epub 2007 Jan 27. Life Sci. 2007. PMID: 17316704

4

The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity.

Copple IM, Goldring CE, Kitteringham NR, Park BK. Copple IM, et al. Toxicology. 2008 Apr 3;246(1):24-33. doi: 10.1016/j.tox.2007.10.029. Epub 2007 Nov 12. Toxicology. 2008. PMID: 18083283 Review.

5

Extract of Ginkgo biloba induces glutamate cysteine ligase catalytic subunit (GCLC).

Liu XP, Goldring CE, Wang HY, Copple IM, Kitteringham NR, Park BK, Wei W. Liu XP, et al. Among authors: copple im. Phytother Res. 2008 Mar;22(3):367-71. doi: 10.1002/ptr.2328. Phytother Res. 2008. PMID: 18167050

6

The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system.

Copple IM, Goldring CE, Jenkins RE, Chia AJ, Randle LE, Hayes JD, Kitteringham NR, Park BK. Copple IM, et al. Hepatology. 2008 Oct;48(4):1292-301. doi: 10.1002/hep.22472. Hepatology. 2008. PMID: 18785192

7

Extract of Ginkgo biloba induces glutathione-S-transferase subunit-P1 in vitro.

Liu XP, Goldring CE, Wang HY, Copple IM, Kitteringham NR, Park BK. Liu XP, et al. Among authors: copple im. Phytomedicine. 2009 May;16(5):451-5. doi: 10.1016/j.phymed.2008.11.001. Epub 2009 Jan 7. Phytomedicine. 2009. PMID: 19131229

8

The keap1-nrf2 cellular defense pathway: mechanisms of regulation and role in protection against drug-induced toxicity.

Copple IM, Goldring CE, Kitteringham NR, Park BK. Copple IM, et al. Handb Exp Pharmacol. 2010;(196):233-66. doi: 10.1007/978-3-642-00663-0_9. Handb Exp Pharmacol. 2010. PMID: 20020265 Review.

9

The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials.

Mercer AE, Copple IM, Maggs JL, O'Neill PM, Park BK. Mercer AE, et al. Among authors: copple im. J Biol Chem. 2011 Jan 14;286(2):987-96. doi: 10.1074/jbc.M110.144188. Epub 2010 Nov 8. J Biol Chem. 2011. PMID: 21059641 Free PMC article.

10

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.

Lister A, Nedjadi T, Kitteringham NR, Campbell F, Costello E, Lloyd B, Copple IM, Williams S, Owen A, Neoptolemos JP, Goldring CE, Park BK. Lister A, et al. Among authors: copple im. Mol Cancer. 2011 Apr 13;10:37. doi: 10.1186/1476-4598-10-37. Mol Cancer. 2011. PMID: 21489257 Free PMC article.

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