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Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species.
Pennathur S, Bergt C, Shao B, Byun J, Kassim SY, Singh P, Green PS, McDonald TO, Brunzell J, Chait A, Oram JF, O'brien K, Geary RL, Heinecke JW. Pennathur S, et al. Among authors: heinecke jw. J Biol Chem. 2004 Oct 8;279(41):42977-83. doi: 10.1074/jbc.M406762200. Epub 2004 Aug 2. J Biol Chem. 2004. PMID: 15292228 Free article.
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Bergt C, Pennathur S, Fu X, Byun J, O'Brien K, McDonald TO, Singh P, Anantharamaiah GM, Chait A, Brunzell J, Geary RL, Oram JF, Heinecke JW. Bergt C, et al. Among authors: heinecke jw. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13032-7. doi: 10.1073/pnas.0405292101. Epub 2004 Aug 23. Proc Natl Acad Sci U S A. 2004. PMID: 15326314 Free PMC article.
270 results